A6VHH0 (PDAD_METM7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pyruvoyl-dependent arginine decarboxylase
Short name=PvlArgDC
EC=4.1.1.19

Cleaved into the following 2 chains:

1. Pyruvoyl-dependent arginine decarboxylase subunit beta
2. Pyruvoyl-dependent arginine decarboxylase subunit alpha

Gene names

Name:	pdaD
Ordered Locus Names:	MmarC7_0829

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]

Taxonomic identifier

426368 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	164 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2. HAMAP MF_01404
Cofactor	Pyruvoyl group By similarity. HAMAP MF_01404
Sequence similarities	Belongs to the pdaD family.

Ontologies

Keywords
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 51	51	Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity		PRO_1000068397
	Chain	52 – 164	113	Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity		PRO_1000068398
Sites
	Site	51 – 52	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	52	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6VHH0 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 208F02EF58F4AEE5	FASTA	164	17,545
	10 20 30 40 50 60 MMKTSAIHSP FEAPNTISLV AGTGDANNPL NAFDMSLLES GIGNLNLIRI SSIMPPKAAI 70 80 90 100 110 120 IPLPKIPQGS LVPTAYGYQI SEVKGETVAA GISVAVPKDK ELCGLIMEYE CIGGKKECED 130 140 150 160 TVRNMAKEGF EMRGWEIDEI ISIASEHTVE NIGCAFAAAA LWYK

References

[1]

"Complete sequence of Methanococcus maripaludis C7." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C7 / ATCC BAA-1331.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000745 Genomic DNA. Translation: ABR65896.1.
RefSeq	YP_001330047.1. NC_009637.1.
3D structure databases
ProteinModelPortal	A6VHH0.
SMR	A6VHH0. Positions 7-164.
ModBase	Search...
Protein-protein interaction databases
STRING	A6VHH0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5327804.
GenomeReviews	Gene locus MmarC7_0829 in contig CP000745_GR.
KEGG	mmz:MmarC7_0829.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG09108.
HOGENOM	HBG539680.
OMA	LVPTAYG.
ProtClustDB	PRK01285.
Enzyme and pathway databases
BioCyc	MMAR426368:MMARC7_0829-MONOMER.
Family and domain databases
HAMAP	MF_01404. PvlArgDC. [Tree]
InterPro	IPR016104. Pyr-dep_his/arg-deCO2ase. IPR016105. Pyr-dep_his/arg-deCO2ase_sand. IPR002724. Pyruvoyl-dep_arg_deCO2ase. [Graphical view]
Gene3D	G3DSA:3.50.20.10. Pyr-dep_his/arg-deCO2ase_sand. 1 hit.
KO	K02626.
Pfam	PF01862. PvlArgDC. 1 hit. [Graphical view]
ProDom	PD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF56271. His_carbxylase. 1 hit.
TIGRFAMs	TIGR00286. TIGR00286. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PDAD_METM7

Accession

Primary (citable) accession number: A6VHH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program