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A6VH99

- A6VH99_METM7

UniProt

A6VH99 - A6VH99_METM7

Protein

Alanine racemase

Gene

MmarC7_0758

Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei37 – 371Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei135 – 1351SubstrateUniRule annotation
    Active sitei266 – 2661Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei313 – 3131Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMMAR426368:GHHL-768-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:MmarC7_0758Imported
    OrganismiMethanococcus maripaludis (strain C7 / ATCC BAA-1331)Imported
    Taxonomic identifieri426368 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
    ProteomesiUP000002298: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei37 – 371N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi426368.MmarC7_0758.

    Structurei

    3D structure databases

    ProteinModelPortaliA6VH99.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiYGHGLER.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6VH99-1 [UniParc]FASTAAdd to Basket

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    MVSHPIWAEI DLSAIKNNIQ EIRRITNPKS QVMAVVKANA YGHGAIEVSK    50
    VCLENGADRL AVARSTEALE LRNAGITCPI LVFGYCTEEE IEKMVENDIT 100
    LTVYSFETAE SIQKIAEKLG KHSKIHIKVD TGMGRLGFLP KKEAIETIKK 150
    IMELKNIKIE GIYTHFADAD NSDKSYTTMQ FSRFTNFLHN LEENEIFIPI 200
    KHASNSAAII DHPETHLNLV RPGIILYGLY PSELVHKERI NLKPAMSLKV 250
    LITHVKEVPE NTKISYGCTF ETKKPSKIAS LPIGYADGFT RMLKDGYVLI 300
    HGSRVPVIGR ICMDQCMIDV SDIENVQVGD VVTIFGTQEN EKIPIEEFGE 350
    KLGTINYELV CMVAGRVPRK YLP 373
    Length:373
    Mass (Da):41,788
    Last modified:August 21, 2007 - v1
    Checksum:iC8D190DB9A17872A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000745 Genomic DNA. Translation: ABR65825.1.
    RefSeqiYP_001329976.1. NC_009637.1.

    Genome annotation databases

    EnsemblBacteriaiABR65825; ABR65825; MmarC7_0758.
    GeneIDi5329353.
    KEGGimmz:MmarC7_0758.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000745 Genomic DNA. Translation: ABR65825.1 .
    RefSeqi YP_001329976.1. NC_009637.1.

    3D structure databases

    ProteinModelPortali A6VH99.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 426368.MmarC7_0758.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR65825 ; ABR65825 ; MmarC7_0758 .
    GeneIDi 5329353.
    KEGGi mmz:MmarC7_0758.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi YGHGLER.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci MMAR426368:GHHL-768-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C7 / ATCC BAA-1331Imported.

    Entry informationi

    Entry nameiA6VH99_METM7
    AccessioniPrimary (citable) accession number: A6VH99
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3