A6VH25 (APGM_METM7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	MmarC7_0684

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]

Taxonomic identifier

426368 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 406	406	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_1000087364

Sequences

	Sequence		Length	Mass (Da)
	A6VH25 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 59B6337DEF10D416	FASTA	406	44,527
	10 20 30 40 50 60 MKAVIFIMDG LGDRPNKDGN TPLKEAKTPI MDKMAKDGIC GLMNAVDVGV RPGSDTAHLA 70 80 90 100 110 120 ILGYDPYTTY TGRGPFEACG VGVTVKPGDI AFRCNFSSVD ENFIVTDRRA GRIENTSELE 130 140 150 160 170 180 KELDGLKIDD VEIIFKESGG YRAALVLRGP GLSDRISDAD PKKEGKRVKE IHPLDDSKEA 190 200 210 220 230 240 KKTAEIVNRL LKIAYEKLDK HPVNEERRKQ NLPVANMIVP RGVGQVPEIM PFTEKTGLKG 250 260 270 280 290 300 ACIAGTGLIK GIAKMVGLDV IDVEGCDGTP NSDLMAKACA IVETLKNYDF ILVNVKGADE 310 320 330 340 350 360 AGHDGNYELK KEIIERIDEM LDYITKNISK DEVYFVISGD HSTPIEEMDH SADPLPIVIW 370 380 390 400 GKSVRVDDVE KFDEFSTHKG GLNWIKGTNI MPILMDLMSI AKKYGA

References

[1]

"Complete sequence of Methanococcus maripaludis C7." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C7 / ATCC BAA-1331.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000745 Genomic DNA. Translation: ABR65751.1.
RefSeq	YP_001329902.1. NC_009637.1.
3D structure databases
ProteinModelPortal	A6VH25.
ModBase	Search...
Protein-protein interaction databases
STRING	A6VH25.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5329569.
GenomeReviews	Gene locus MmarC7_0684 in contig CP000745_GR.
KEGG	mmz:MmarC7_0684.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04733.
HOGENOM	HBG463247.
OMA	DIAFRCN.
ProtClustDB	PRK04024.
Enzyme and pathway databases
BioCyc	MMAR426368:MMARC7_0684-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METM7

Accession

Primary (citable) accession number: A6VH25

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program