A6VH12 (DCD_METM7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	MmarC7_0671

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]

Taxonomic identifier

426368 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 206	206	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009753

Sequences

	Sequence		Length	Mass (Da)
	A6VH12 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 7ACE169C6318750A	FASTA	206	23,546
	10 20 30 40 50 60 MILSDKDIFD YVNSKRVLIE PFNSKFVGPC SYDVTLGSEF IKYKEDVYDL KKSLSHNKFE 70 80 90 100 110 120 IENSIMVCPL NHHLDETIIE NYKEKYNVDC IVSGGLLGTT NEYVELPNDV CAQYQGRSSF 130 140 150 160 170 180 GRVFLQTHQT AGWIDSGFRG KITLEIVAYD KPVILYKNQR VGQLIFSKSL SPADVGYSDR 190 200 KYSKYAGQKS VMASLIKKDF EIDEEE

References

[1]

"Complete sequence of Methanococcus maripaludis C7." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C7 / ATCC BAA-1331.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000745 Genomic DNA. Translation: ABR65738.1.
RefSeq	YP_001329889.1. NC_009637.1.
3D structure databases
ProteinModelPortal	A6VH12.
SMR	A6VH12. Positions 1-199.
ModBase	Search...
Protein-protein interaction databases
STRING	A6VH12.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5329581.
GenomeReviews	Gene locus MmarC7_0671 in contig CP000745_GR.
KEGG	mmz:MmarC7_0671.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG05800.
HOGENOM	HBG553199.
OMA	HQTAGWI.
ProtClustDB	CLSK876187.
Enzyme and pathway databases
BioCyc	MMAR426368:MMARC7_0671-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METM7

Accession

Primary (citable) accession number: A6VH12

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program