A6VGY0 (AROD_METM7) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 27.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 3-dehydroquinate dehydratase Short name=3-dehydroquinase EC=4.2.1.10 Alternative name(s): Type I DHQase | ||||
| Gene names |
| ||||
| Organism | Methanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 426368 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus |
Protein attributes
| Sequence length | 218 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | 3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214 |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214 |
| Sequence similarities | Belongs to the type-I 3-dehydroquinase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis |
| Ligand | Schiff base |
| Molecular function | Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | 3-dehydroquinate dehydratase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 218 | 218 | 3-dehydroquinate dehydratase HAMAP MF_00214 | PRO_1000043174 | |||||
Sites | |||||||||
| Active site | 116 | 1 | Proton acceptor By similarity | ||||||
| Active site | 142 | 1 | Schiff-base intermediate with substrate By similarity | ||||||
Sequences
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References
| [1] | "Complete sequence of Methanococcus maripaludis C7." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C7 / ATCC BAA-1331. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000745 Genomic DNA. Translation: ABR65706.1. |
| RefSeq | YP_001329857.1. NC_009637.1. |
3D structure databases | |
| ProteinModelPortal | A6VGY0. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A6VGY0. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 5328462. |
| GenomeReviews | Gene locus MmarC7_0639 in contig CP000745_GR. |
| KEGG | mmz:MmarC7_0639. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | arNOG12575. |
| HOGENOM | HBG732926. |
| OMA | IAKIAVM. |
| ProtClustDB | CLSK876583. |
Enzyme and pathway databases | |
| BioCyc | MMAR426368:MMARC7_0639-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00214. AroD. [Tree] |
| InterPro | IPR018508. 3-dehydroquinate_DH_AS. IPR013785. Aldolase_TIM. IPR001381. DHquinase_I. [Graphical view] |
| Gene3D | G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. |
| KO | K03785. |
| Pfam | PF01487. DHquinase_I. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01093. AroD. 1 hit. |
| PROSITE | PS01028. DEHYDROQUINASE_I. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AROD_METM7 | ||||||||
| Accession | Primary (citable) accession number: A6VGY0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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