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A6VGS0 (AROC_METM7) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:MmarC7_0578
OrganismMethanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]
Taxonomic identifier426368 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 373373Chorismate synthase HAMAP MF_00300
PRO_0000322434

Sequences

Sequence LengthMass (Da)Tools
A6VGS0 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 4EF051ADD6724EAB

FASTA37340,796
        10         20         30         40         50         60 
MNTFGDNFRV TTWGESHGKA LGAVIDGCPA NLPISEQDIQ NELNRRRPGY SIFSTPRKEE 

        70         80         90        100        110        120 
DKVEILSGIF EGKTTGTPIS GLVFNKGQKS KDYSKIKDTP RPGHADLNYF LKYGNYDYRG 

       130        140        150        160        170        180 
GGRSSGRTTI GNVIGGAVAK KLIEFTHNIK IIGYSTKIGK IKGDFDYYKN PKFFESDSNI 

       190        200        210        220        230        240 
EKLLKKIENN PLRCPSKNSD EMKDYVIDAM DKKDSVGGII EIIIKGIPQG VGNPVFNKLE 

       250        260        270        280        290        300 
GKLGSAFIGI NAVKGFEIGR GFEASELYGS EMNDAYHIYE NSIKEMTNNA GGIIGGISTG 

       310        320        330        340        350        360 
SPVVLRVSIK PTPSISKIQD SMNLISNKDE KIEIGGRHDP IIVPRVIPVL ESMAAITVAD 

       370 
LMISSGYINP CRI

« Hide

References

[1]"Complete sequence of Methanococcus maripaludis C7."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C7 / ATCC BAA-1331.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000745 Genomic DNA. Translation: ABR65646.1.
RefSeqYP_001329797.1. NC_009637.1.

3D structure databases

ProteinModelPortalA6VGS0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6VGS0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5328585.
GenomeReviewsGene locus MmarC7_0578 in contig CP000745_GR.
KEGGmmz:MmarC7_0578.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04618.
HOGENOMHBG292336.
OMASRFTTQR.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycMMAR426368:MMARC7_0578-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_METM7
AccessionPrimary (citable) accession number: A6VGS0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: November 16, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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