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A6VGC7 (FUCA_METM7) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
L-fuculose phosphate aldolase

EC=4.1.2.17
Alternative name(s):
L-fuculose-1-phosphate aldolase
Gene names
Name:fucA
Ordered Locus Names:MmarC7_0434
OrganismMethanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]
Taxonomic identifier426368 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length180 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible aldol cleavage of L-fuculose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde By similarity.

Catalytic activity

L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.

Cofactor

Binds 1 zinc ion per subunit Potential.

Pathway

Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 3/3.

Cofactor biosynthesis; coenzyme F420 biosynthesis.

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the aldolase class II family. AraD/FucA subfamily.

Ontologies

Keywords
   LigandMetal-binding
Zinc
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processfucose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionL-fuculose-phosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 180180L-fuculose phosphate aldolase
PRO_0000342596

Sites

Metal binding681Zinc By similarity
Metal binding871Zinc By similarity
Metal binding891Zinc By similarity
Metal binding1471Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A6VGC7 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: D63FD14CF12562E1

FASTA18020,039
        10         20         30         40         50         60 
MDLINFIKIC HLLYDRKYVV GSGGNVSIRD GNHIYITPTG SILGFLNEED VCIVDLNGNI 

        70         80         90        100        110        120 
IKGKPTSELN MHLKIYQNKD CVNAIVHTHS MYCTAFSALD KKLELFTPEA EIVVKKIAYV 

       130        140        150        160        170        180 
DYSPCGSLEL AENVSSCVED SIILKNHGIV TVGKDITEAY VKTEVLEEIA QLNYIINNLK 

« Hide

References

[1]"Complete sequence of Methanococcus maripaludis C7."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C7 / ATCC BAA-1331.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000745 Genomic DNA. Translation: ABR65503.1.
RefSeqYP_001329654.1. NC_009637.1.

3D structure databases

ProteinModelPortalA6VGC7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING426368.MmarC7_0434.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR65503; ABR65503; MmarC7_0434.
GeneID5328172.
KEGGmmz:MmarC7_0434.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0235.
HOGENOMHOG000218182.
KOK01628.
OMAPVVWESS.
ProtClustDBCLSK876567.

Enzyme and pathway databases

BioCycMMAR426368:GHHL-436-MONOMER.
UniPathwayUPA00071.
UPA00563; UER00626.

Family and domain databases

Gene3D3.40.225.10. 1 hit.
InterProIPR001303. Aldolase_II/adducin_N.
[Graphical view]
PfamPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMSSF53639. SSF53639. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFUCA_METM7
AccessionPrimary (citable) accession number: A6VGC7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: August 21, 2007
Last modified: October 16, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways