A6VFZ9 (SURE_METM7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	MmarC7_0305

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]

Taxonomic identifier

426368 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 264	264	5'-nucleotidase surE HAMAP MF_00060		PRO_0000335294
Sites
	Metal binding	10	1	Divalent metal cation By similarity
	Metal binding	11	1	Divalent metal cation By similarity
	Metal binding	43	1	Divalent metal cation By similarity
	Metal binding	99	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6VFZ9 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: E6F2C79BE069E3C7	FASTA	264	29,114
	10 20 30 40 50 60 MTMEILLVND DGIYSNGLLA LKNVIGEEFD ANVTVVAPTN QQSGIGRAIS LFEPLRITKT 70 80 90 100 110 120 KLADCSEGYA VSGTPTDCVV LGIHQVLKKV PDYVISGINI GENLGTEITT SGTLGAAFEG 130 140 150 160 170 180 AHHGAKALAC SLQVTMDHLK FKEGESPIEF LTTARIVKNV FKKFLGDEFP CDVVNINVPD 190 200 210 220 230 240 NATENTPVEI TKLAKRMYSM HVEERIDPRS RSYYWLDGYP VMDEEDGTDV YAVRNKRNVS 250 260 VTPLTLDNTA KNLDEFKEKY AKKF

References

[1]

"Complete sequence of Methanococcus maripaludis C7." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C7 / ATCC BAA-1331.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000745 Genomic DNA. Translation: ABR65375.1.
RefSeq	YP_001329526.1. NC_009637.1.
3D structure databases
ProteinModelPortal	A6VFZ9.
ModBase	Search...
Protein-protein interaction databases
STRING	A6VFZ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5328266.
GenomeReviews	Gene locus MmarC7_0305 in contig CP000745_GR.
KEGG	mmz:MmarC7_0305.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG05083.
HOGENOM	HBG600532.
OMA	NINIPEN.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	MMAR426368:MMARC7_0305-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_METM7

Accession

Primary (citable) accession number: A6VFZ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program