Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

5'-nucleotidase SurE

Gene

surE

Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi10 – 101Divalent metal cationUniRule annotation
Metal bindingi11 – 111Divalent metal cationUniRule annotation
Metal bindingi43 – 431Divalent metal cationUniRule annotation
Metal bindingi99 – 991Divalent metal cationUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR426368:GHHL-306-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:MmarC7_0305
OrganismiMethanococcus maripaludis (strain C7 / ATCC BAA-1331)
Taxonomic identifieri426368 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000002298 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2642645'-nucleotidase SurEPRO_0000335294Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi426368.MmarC7_0305.

Structurei

3D structure databases

ProteinModelPortaliA6VFZ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02303. Archaea.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiEEKFDKR.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

A6VFZ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMEILLVND DGIYSNGLLA LKNVIGEEFD ANVTVVAPTN QQSGIGRAIS
60 70 80 90 100
LFEPLRITKT KLADCSEGYA VSGTPTDCVV LGIHQVLKKV PDYVISGINI
110 120 130 140 150
GENLGTEITT SGTLGAAFEG AHHGAKALAC SLQVTMDHLK FKEGESPIEF
160 170 180 190 200
LTTARIVKNV FKKFLGDEFP CDVVNINVPD NATENTPVEI TKLAKRMYSM
210 220 230 240 250
HVEERIDPRS RSYYWLDGYP VMDEEDGTDV YAVRNKRNVS VTPLTLDNTA
260
KNLDEFKEKY AKKF
Length:264
Mass (Da):29,114
Last modified:August 21, 2007 - v1
Checksum:iE6F2C79BE069E3C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000745 Genomic DNA. Translation: ABR65375.1.
RefSeqiWP_011976711.1. NC_009637.1.

Genome annotation databases

EnsemblBacteriaiABR65375; ABR65375; MmarC7_0305.
GeneIDi5328266.
KEGGimmz:MmarC7_0305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000745 Genomic DNA. Translation: ABR65375.1.
RefSeqiWP_011976711.1. NC_009637.1.

3D structure databases

ProteinModelPortaliA6VFZ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi426368.MmarC7_0305.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR65375; ABR65375; MmarC7_0305.
GeneIDi5328266.
KEGGimmz:MmarC7_0305.

Phylogenomic databases

eggNOGiarCOG02303. Archaea.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiEEKFDKR.

Enzyme and pathway databases

BioCyciMMAR426368:GHHL-306-MONOMER.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSURE_METM7
AccessioniPrimary (citable) accession number: A6VFZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.