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Reviewed, UniProtKB/Swiss-Prot A6VFQ9 (DNLI_METM7)

Last modified November 25, 2008. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    DNA ligase
    EC=6.5.1.1
Alternative name(s):
    Polydeoxyribonucleotide synthase [ATP]
Gene names
Name: lig
Ordered Locus Names: MmarC7_0215
OrganismMethanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]
Taxonomic identifier426368 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length573 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

This protein seals, during DNA replication, DNA recombination and DNA repair, nicks in double-stranded DNA By similarity.

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

Sequence similarities

Belongs to the ATP-dependent DNA ligase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 573573DNA ligase
PRO_1000049871

Sites

Active site2521N6-AMP-lysine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
A6VFQ9-1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 5B28D05EF1F134E1

FASTA57365,814
        10         20         30         40         50         60 
MLFIDFCKIL DKIEKTTKRL EKTDYFVELI DFIKTNGKPE NLKQVSQITI GRVFAEFENK 

        70         80         90        100        110        120 
EIGIGPNLLL EAVKTTGISE KDLKSKIKET GDIGIAVENL SSNIKQVSLF SQALTLEEVY 

       130        140        150        160        170        180 
STLKKLSEIE GNSSQKKKTR IISNLLILAT PVESRYISRL ILEDMRIGMN IPTILASFSN 

       190        200        210        220        230        240 
YFNINKETVE KIYAVTNDIG LLGEKLISGS NIENDSELQL KVFRPIKPML AQLTPSIEAA 

       250        260        270        280        290        300 
IIETKMPQFE TKYDGARVQV HKSDGNVKIY SRRLENITNS VPELVEEIKK IDIDNIILEG 

       310        320        330        340        350        360 
ECVAMDLSSG KPRPFQDILR RFRRKYDIDK MAEKIALRIY FFDVLYYEKG LIDTPLKDRR 

       370        380        390        400        410        420 
EILEKLFGTN NWDTELSKIE KEIFSNKMLF SSFKLNSDDP ILAKEFFNWS LSIGHEGIMI 

       430        440        450        460        470        480 
KNPDAPYTPG SRVKTMYKVK PTLENLDVVV TRAKIGMGKR KDWYGSYEIS VKDYEDNLHV 

       490        500        510        520        530        540 
IGNVGTGLTE DDLEKLTKIV NEIKIEDLGE EVILEPKIVL EVTYEEIQTS EKYEMGYALR 

       550        560        570 
FPRVVQIRED KSINDINTLD DVKKIYEIER NRK 

« Hide

References

[1]"Complete sequence of Methanococcus maripaludis C7."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000745 Genomic DNA. Translation: ABR65285.1.
RefSeqYP_001329436.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5328957.
GenomeReviewsGene locus MmarC7_0215 in contig CP000745_GR.
KEGGmmz:MmarC7_0215.

Organism-specific databases

CMRSearch...

Family and domain databases

HAMAPMF_00407.
[Tree]
InterProIPR000977. DNA_ligase.
IPR012309. DNA_ligase_A_C.
IPR012310. DNA_ligase_A_M.
IPR012308. DNA_ligase_A_N.
IPR016059. DNA_ligase_CS.
IPR012340. NA-bd_OB-fold.
[Graphical view]
Gene3DG3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDNLI_METM7
AccessionPrimary (citable) accession number: A6VFQ9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: November 25, 2008
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents