Reviewed, UniProtKB/Swiss-Prot A6VFH0 (RNP2_METM7)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 2
      Short name=RNase P component 2
    EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	MmarC7_0126

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331) [Complete proteome] [HAMAP]

Taxonomic identifier

426368 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	130 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential. HAMAP MF_00755
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 130	130	Ribonuclease P protein component 2 HAMAP MF_00755		PRO_1000046623

Sequences

	Sequence		Length	Mass (Da)
	A6VFH0-1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 1EE387A33EA3BC29	FASTA	130	15,213
	10 20 30 40 50 60 MLKTLPPTLR EKKRYVALEI IFEDELFQKD VIAIVRNALM NYSGVLGCSK ANPWLIDYNH 70 80 90 100 110 120 PYGILRISRD EVDNLRSSLS LSNEHRKKPI NIHIIGISNS VKHIREKFLH VPHEPYYKVI 130 QKLKKKGPKR

References

[1]

"Complete sequence of Methanococcus maripaludis C7." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000745 Genomic DNA. Translation: ABR65196.1.
RefSeq	YP_001329347.1.
3D structure databases
SMR	A6VFH0. Positions 2-110.
ModBase	Search...
Protein-protein interaction databases
STRING	A6VFH0.
Genome annotation databases
GeneID	5328562.
GenomeReviews	Gene locus MmarC7_0126 in contig CP000745_GR.
KEGG	mmz:MmarC7_0126.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG11703.
HOGENOM	HBG551631.
OMA	LKTLPPT.
Family and domain databases
HAMAP	MF_00755. RNase_P_2. [Tree]
InterPro	IPR016434. RNase_P_comp-2. IPR002759. RNase_P_related. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF004952. RNase_P_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP2_METM7

Accession

Primary (citable) accession number: A6VFH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 21, 2007
Last modified:	January 19, 2010
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)