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Protein

60 kDa chaperonin

Gene

groL

Organism
Pseudomonas aeruginosa (strain PA7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:PSPA7_4956
OrganismiPseudomonas aeruginosa (strain PA7)
Taxonomic identifieri381754 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000001582 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000258181 – 54760 kDa chaperoninAdd BLAST547

Proteomic databases

PRIDEiA6VB57.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA6VB57.
SMRiA6VB57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A6VB57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKEVKFGD SARKKMLVGV NVLADAVKAT LGPKGRNVVL DKSFGAPTIT
60 70 80 90 100
KDGVSVAKEI ELKDKFENMG AQLVKDVASK ANDAAGDGTT TATVLAQAIV
110 120 130 140 150
NEGLKAVAAG MNPMDLKRGI DKATVAIVAQ LKELAKPCAD TKAIAQVGTI
160 170 180 190 200
SANSDESIGQ IIAEAMEKVG KEGVITVEEG SGLENELSVV EGMQFDRGYL
210 220 230 240 250
SPYFVNKPDT MAAELDSPLL LLVDKKISNI REMLPVLEAV AKAGRPLLIV
260 270 280 290 300
AEDVEGEALA TLVVNNMRGI VKVAAVKAPG FGDRRKAMLQ DIAILTGGTV
310 320 330 340 350
ISEEVGLSLE GATLEHLGNA KRVVINKENT TIIDGAGVQA DIEARVLQIR
360 370 380 390 400
KQIEETTSDY DREKLQERLA KLAGGVAVIK VGAATEVEMK EKKARVEDAL
410 420 430 440 450
HATRAAVEEG VVPGGGVALV RALQAIEGLK GDNEEQNVGI ALLRRAVEAP
460 470 480 490 500
LRQIVANAGD EPSVVVDKVK QGSGNYGFNA ATGVYGDMIE MGILDPAKVT
510 520 530 540
RSALQAAASI GGLMITTEAM VAEIVEDKPA MGGMPDMGGM GGMGGMM
Length:547
Mass (Da):57,070
Last modified:August 21, 2007 - v1
Checksum:i6AF8F2B7A913EAF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000744 Genomic DNA. Translation: ABR83794.1.
RefSeqiWP_012077175.1. NC_009656.1.

Genome annotation databases

EnsemblBacteriaiABR83794; ABR83794; PSPA7_4956.
KEGGipap:PSPA7_4956.

Similar proteinsi

Entry informationi

Entry nameiCH60_PSEA7
AccessioniPrimary (citable) accession number: A6VB57
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: November 22, 2017
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families