Skip Header

Contribute Send feedback
Read comments (?) or add your own

A6VAE3 (ACKA_PSEA7) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:PSPA7_4684
OrganismPseudomonas aeruginosa (strain PA7) [Complete proteome] [HAMAP]
Taxonomic identifier381754 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Acetate kinase HAMAP MF_00020
PRO_1000002246

Sequences

Sequence LengthMass (Da)Tools
A6VAE3 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 2AB2FFBB0C1526A1

FASTA39442,363
        10         20         30         40         50         60 
MPSRNILVIN CGSSSIKFAL VNEAHSLFPL HGLAERLGSR DAVLRWKRGG DSDSLMIPNA 

        70         80         90        100        110        120 
DHRAALAQLL PMVQNAAGGK LHGIGHRVVH GGELFTHATR LDGRVIEAIR ATAPLAPLHN 

       130        140        150        160        170        180 
PANLQGIEAA MTLFPGLPHV AVFDTAFHQS LPEHAYRYAL PEALYREHGV RRYGFHGTSH 

       190        200        210        220        230        240 
RYVSHRAAEM AGLAVGDSSW LSAHLGNGSS TCAIVNGQSL DTSMGLTPLE GLVMGTRSGD 

       250        260        270        280        290        300 
VDPNLHSHLA RTLGWSLERI DSMLNNESGL LGLSNLSNDM RTLEQEREQG HPGAALAIEV 

       310        320        330        340        350        360 
FCYRLAKSLA AMSCALPQLD GVIFTGGIGE NSPLVRAKTV AHLRLFDLRL DQEANARCVR 

       370        380        390 
GVAGPIQATG HPRVLVIPTN EERQIALDTL ALLD

« Hide

References

[1]Dodson R.J., Harkins D., Paulsen I.T.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PA7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000744 Genomic DNA. Translation: ABR83754.1.
RefSeqYP_001350028.1. NC_009656.1.

3D structure databases

ProteinModelPortalA6VAE3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6VAE3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5357808.
GenomeReviewsGene locus PSPA7_4684 in contig CP000744_GR.
KEGGpap:PSPA7_4684.
PATRIC19830934. VBIPseAer80442_4467.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMAAISHIAR.
PhylomeDBA6VAE3.
ProtClustDBPRK00180.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_PSEA7
AccessionPrimary (citable) accession number: A6VAE3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents