ID   A6V9H4_PSEA7            Unreviewed;       497 AA.
AC   A6V9H4;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE            EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN   OrderedLocusNames=PSPA7_4356 {ECO:0000313|EMBL:ABR82122.1};
OS   Pseudomonas aeruginosa (strain PA7).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=381754 {ECO:0000313|EMBL:ABR82122.1, ECO:0000313|Proteomes:UP000001582};
RN   [1] {ECO:0000313|EMBL:ABR82122.1, ECO:0000313|Proteomes:UP000001582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PA7 {ECO:0000313|EMBL:ABR82122.1,
RC   ECO:0000313|Proteomes:UP000001582};
RA   Dodson R.J., Harkins D., Paulsen I.T.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABR82122.1, ECO:0000313|Proteomes:UP000001582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PA7 {ECO:0000313|EMBL:ABR82122.1,
RC   ECO:0000313|Proteomes:UP000001582};
RX   PubMed=20107499; DOI=10.1371/journal.pone.0008842;
RA   Roy P.H., Tetu S.G., Larouche A., Elbourne L., Tremblay S., Ren Q.,
RA   Dodson R., Harkins D., Shay R., Watkins K., Mahamoud Y., Paulsen I.T.;
RT   "Complete genome sequence of the multiresistant taxonomic outlier
RT   Pseudomonas aeruginosa PA7.";
RL   PLoS ONE 5:E8842-E8842(2010).
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000744; ABR82122.1; -; Genomic_DNA.
DR   RefSeq; WP_012076764.1; NC_009656.1.
DR   AlphaFoldDB; A6V9H4; -.
DR   KEGG; pap:PSPA7_4356; -.
DR   HOGENOM; CLU_005391_1_2_6; -.
DR   Proteomes; UP000001582; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07130; ALDH_F7_AASADH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR044638; ALDH7A1-like.
DR   PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          21..479
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        253
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   497 AA;  53784 MW;  1A0EFD4D8DDCF120 CRC64;
     MIDGLLRSLG LDPADFGEGE HAVHTPVDGS RLAMLRLEGR DAAGARLERA EQAFRAWRQV
     PAPRRGELVR LFGEELRRHK VQLGELVSWE AGKITQEGLG EVQEMIDICD FAVGLSRQLY
     GLTIASERPG HHMRETWHPL GVVGVISAFN FPVAVWSWNA ALALVCGNAV VWKPSEKTPL
     TALACQALFE RAARAFGADA PAHLSQLLIG GREAGEALAD DPRVALLSAT GSTRMGREVA
     PRVAARFGRC ILELGGNNAM ILAPSADLDL AVRGILFGAV GTAGQRCTTL RRLIAHESVK
     DEIVARLKTA YSKVRIGHPL EGNLVGPLID AHSYRAMQDT LARAREQGGQ VFGGERQLRE
     RYPDAYYVSP AIVEMPGQTE VVRTETFAPI LYVIGYRDFD EALRLNNEVP QGLSSCIFTT
     DLREAERFQG AAGSDCGIAN VNIGTSGAEI GGAFGGEKDT GGGRESGSDA WKAYMRRQTN
     TVNYSRELPL AQGITFD
//