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A6V7F4 (GLSA_PSEA7) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutaminase
EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:PSPA7_3635
OrganismPseudomonas aeruginosa (strain PA7) [Complete proteome] [HAMAP]
Taxonomic identifier381754 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Sequence caution

The sequence ABR84204.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302Glutaminase HAMAP-Rule MF_00313
PRO_0000336035

Sites

Binding site611Substrate By similarity
Binding site1111Substrate By similarity
Binding site1551Substrate By similarity
Binding site1621Substrate By similarity
Binding site1861Substrate By similarity
Binding site2381Substrate By similarity
Binding site2561Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A6V7F4 [UniParc].

Last modified May 20, 2008. Version 2.
Checksum: 3F9DFC4646FE2DFA

FASTA30233,027
        10         20         30         40         50         60 
MQQLLNEILD EVRPLIGRGK VADYIPALAG VEPDQLGIAV YSRDGELFHA GDALRPFSIQ 

        70         80         90        100        110        120 
SISKVFSLVQ AIQHSGEDIW QRLGHEPSGQ PFNSLVQLEF ERGRPRNPFI NAGALVICDI 

       130        140        150        160        170        180 
NQSRFAAPAQ SMRDFVRRLC GNPEVVSDSV VARSEYQHRS RNAAAAYLMK SFGNFHNDVE 

       190        200        210        220        230        240 
AVLLSYFHHC ALRMSCVDLA RAFCFLADKG FCKHSGEQVL NERQTKQVNA IMATSGLYDE 

       250        260        270        280        290        300 
AGNFAYRVGL PGKSGVGGGI IAVVPGRFTV CVWSPELNGA GNSLAGIAAL EKLSERIGWS 


IF

« Hide

References

[1]Dodson R.J., Harkins D., Paulsen I.T.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PA7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000744 Genomic DNA. Translation: ABR84204.1. Different initiation.
RefSeqYP_001348989.1. NC_009656.1.

3D structure databases

ProteinModelPortalA6V7F4.
ModBaseSearch...

Protein-protein interaction databases

STRING381754.PSPA7_3635.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR84204; ABR84204; PSPA7_3635.
GeneID5354129.
KEGGpap:PSPA7_3635.
PATRIC19828918. VBIPseAer80442_3466.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycPAER381754:GHMY-3635-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. PBP_transp_fold. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_PSEA7
AccessionPrimary (citable) accession number: A6V7F4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 29, 2013
This is version 36 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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