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A6V7F4

- GLSA_PSEA7

UniProt

A6V7F4 - GLSA_PSEA7

Protein

Glutaminase

Gene

glsA

Organism
Pseudomonas aeruginosa (strain PA7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 2 (20 May 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei61 – 611SubstrateUniRule annotation
    Binding sitei111 – 1111SubstrateUniRule annotation
    Binding sitei155 – 1551SubstrateUniRule annotation
    Binding sitei162 – 1621SubstrateUniRule annotation
    Binding sitei186 – 1861SubstrateUniRule annotation
    Binding sitei238 – 2381SubstrateUniRule annotation
    Binding sitei256 – 2561Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciPAER381754:GHMY-3635-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:PSPA7_3635
    OrganismiPseudomonas aeruginosa (strain PA7)
    Taxonomic identifieri381754 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000001582: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 302302GlutaminasePRO_0000336035Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi381754.PSPA7_3635.

    Structurei

    3D structure databases

    ProteinModelPortaliA6V7F4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6V7F4-1 [UniParc]FASTAAdd to Basket

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    MQQLLNEILD EVRPLIGRGK VADYIPALAG VEPDQLGIAV YSRDGELFHA    50
    GDALRPFSIQ SISKVFSLVQ AIQHSGEDIW QRLGHEPSGQ PFNSLVQLEF 100
    ERGRPRNPFI NAGALVICDI NQSRFAAPAQ SMRDFVRRLC GNPEVVSDSV 150
    VARSEYQHRS RNAAAAYLMK SFGNFHNDVE AVLLSYFHHC ALRMSCVDLA 200
    RAFCFLADKG FCKHSGEQVL NERQTKQVNA IMATSGLYDE AGNFAYRVGL 250
    PGKSGVGGGI IAVVPGRFTV CVWSPELNGA GNSLAGIAAL EKLSERIGWS 300
    IF 302
    Length:302
    Mass (Da):33,027
    Last modified:May 20, 2008 - v2
    Checksum:i3F9DFC4646FE2DFA
    GO

    Sequence cautioni

    The sequence ABR84204.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000744 Genomic DNA. Translation: ABR84204.1. Different initiation.
    RefSeqiYP_001348989.1. NC_009656.1.

    Genome annotation databases

    EnsemblBacteriaiABR84204; ABR84204; PSPA7_3635.
    GeneIDi5354129.
    KEGGipap:PSPA7_3635.
    PATRICi19828918. VBIPseAer80442_3466.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000744 Genomic DNA. Translation: ABR84204.1 . Different initiation.
    RefSeqi YP_001348989.1. NC_009656.1.

    3D structure databases

    ProteinModelPortali A6V7F4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 381754.PSPA7_3635.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR84204 ; ABR84204 ; PSPA7_3635 .
    GeneIDi 5354129.
    KEGGi pap:PSPA7_3635.
    PATRICi 19828918. VBIPseAer80442_3466.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci PAER381754:GHMY-3635-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Dodson R.J., Harkins D., Paulsen I.T.
      Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PA7.

    Entry informationi

    Entry nameiGLSA_PSEA7
    AccessioniPrimary (citable) accession number: A6V7F4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3