A6V6I2 (A6V6I2_PSEA7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654

Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654

Gene names

Name:	pqqC HAMAP MF_00654 EMBL ABR81006.1
Ordered Locus Names:	PSPA7_3307

Organism

Pseudomonas aeruginosa (strain PA7) [Complete proteome] [HAMAP]

Taxonomic identifier

381754 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654
Catalytic activity	6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654
Pathway	Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654
Sequence similarities	Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
Biological process	PQQ biosynthesis HAMAP MF_00654
Molecular function	Oxidoreductase HAMAP MF_00654
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrroloquinoline quinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	pyrroloquinoline-quinone synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6V6I2 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 023728A8864C8B57	FASTA	270	31,541
	10 20 30 40 50 60 MPVASKWPGM ACTSSCRGTD MSRAAMDRAE FERALRDKGR YYHIHHPFHV AMYEGRASRE 70 80 90 100 110 120 QIQGWVANRF YYQLNIPLKD AAILANCPDR EVRREWVQRI LDHDGAPGEA GGIEAWLRLA 130 140 150 160 170 180 EAVGLEREQV LSEERVLPGV RFAVDAYVNF ARRASWQEAA SSSLTELFAP QIHQSRLDSW 190 200 210 220 230 240 PRHYPWIEAA GYEYFRSRLA QARRDVEHGL RITLEHYRTR EAQERMLEIL QFKLDVLWSM 250 260 270 LDAMSMAYEL ERPPYHTVTR ERVWHRGLAP

References

[1]	Dodson R.J., Harkins D., Paulsen I.T. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000744 Genomic DNA. Translation: ABR81006.1.
RefSeq	YP_001348667.1. NC_009656.1.
3D structure databases
ProteinModelPortal	A6V6I2.
SMR	A6V6I2. Positions 31-265.
ModBase	Search...
Protein-protein interaction databases
STRING	A6V6I2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5356053.
GenomeReviews	Gene locus PSPA7_3307 in contig CP000744_GR.
KEGG	pap:PSPA7_3307.
PATRIC	19828272. VBIPseAer80442_3148.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG5424.
HOGENOM	HBG288944.
OMA	DSWPQHY.
ProtClustDB	PRK05157.
Family and domain databases
HAMAP	MF_00654. PQQ_syn_PqqC. [Tree]
InterPro	IPR016084. Haem_Oase-like_multi-hlx. IPR011845. PQQ_synth_PqqC. IPR004305. TENA/THI4/PQQ_synthPqqC_dom. [Graphical view]
Gene3D	G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KO	K06137.
Pfam	PF03070. TENA_THI-4. 1 hit. [Graphical view]
SUPFAM	SSF48613. Heme_oxygenase. 1 hit.
TIGRFAMs	TIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6V6I2_PSEA7

Accession

Primary (citable) accession number: A6V6I2

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)