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Protein

Trans-aconitate 2-methyltransferase

Gene

tam

Organism
Pseudomonas aeruginosa (strain PA7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPAER381754:GHMY-2668-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Trans-aconitate 2-methyltransferaseUniRule annotation (EC:2.1.1.144UniRule annotation)
Gene namesi
Name:tamUniRule annotation
Ordered Locus Names:PSPA7_2668
OrganismiPseudomonas aeruginosa (strain PA7)
Taxonomic identifieri381754 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000001582 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 275275Trans-aconitate 2-methyltransferasePRO_1000056571Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA6V4P3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. Tam family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000125295.
KOiK00598.
OMAiWHTVYQH.

Family and domain databases

Gene3Di1.10.150.290. 1 hit.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

A6V4P3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRDDLRCRA GNETHWDPTA YMQFARLRQR PVVELLDHVD LYSPERIYDL
60 70 80 90 100
GCGTGIATEL LARRWPQAEL HGVDSSAEML EEAARLPIRA SWERANLQHW
110 120 130 140 150
CAERPASLLF AAAVLHFIER HCSLLPRLLG QLSPGGCLAA HMPNWRDASW
160 170 180 190 200
YRLMLDALDS AGPGGTPLGS PTLRYLMQQR NVLSLDNYYR LLAPLCAEVD
210 220 230 240 250
IWETEHLQVV DGNDPIFDWV KVSALRPVLG ELDEEARRRF LDRYLDLLHR
260 270
YYPQELDGRT LFPFRRVFVV ASLRR
Length:275
Mass (Da):31,702
Last modified:August 21, 2007 - v1
Checksum:i893D207AE41665AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000744 Genomic DNA. Translation: ABR84604.1.
RefSeqiWP_012075509.1. NC_009656.1.

Genome annotation databases

EnsemblBacteriaiABR84604; ABR84604; PSPA7_2668.
KEGGipap:PSPA7_2668.
PATRICi19827066. VBIPseAer80442_2546.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000744 Genomic DNA. Translation: ABR84604.1.
RefSeqiWP_012075509.1. NC_009656.1.

3D structure databases

ProteinModelPortaliA6V4P3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR84604; ABR84604; PSPA7_2668.
KEGGipap:PSPA7_2668.
PATRICi19827066. VBIPseAer80442_2546.

Phylogenomic databases

HOGENOMiHOG000125295.
KOiK00598.
OMAiWHTVYQH.

Enzyme and pathway databases

BioCyciPAER381754:GHMY-2668-MONOMER.

Family and domain databases

Gene3Di1.10.150.290. 1 hit.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTAM_PSEA7
AccessioniPrimary (citable) accession number: A6V4P3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.