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A6V4G3 (A6V4G3_PSEA7) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL ABR82501.1
Ordered Locus Names:PSPA7_2584 EMBL ABR82501.1
OrganismPseudomonas aeruginosa (strain PA7) [Complete proteome] [HAMAP] EMBL ABR82501.1
Taxonomic identifier381754 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Sequences

Sequence LengthMass (Da)Tools
A6V4G3 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: C314448CF03C75F7

FASTA41845,605
        10         20         30         40         50         60 
MGYQKIQVPA TGDKITVNAD MSLSVPKNPI IPFIEGDGIG VDISPVMIKV VDAAVEKAYK 

        70         80         90        100        110        120 
GERKIAWMEV YAGEKATQVY DQDTWLPQET LDAVRDYVVS IKGPLTTPVG GGIRSLNVAL 

       130        140        150        160        170        180 
RQQLDLYVCQ RPVRWFEGVP SPVKKPGDVD MVIFRENSED IYAGVEWKAG SPEAEKVIKF 

       190        200        210        220        230        240 
LTEEMGVKKI RFTENCGIGI KPVSQEGTKR LVRKALQYAV DNDRSSVTLV HKGNIMKFTE 

       250        260        270        280        290        300 
GAFKDWGYEV ARDEFGAELL DGGPWMQFKN PKTGRNVVVK DVIADAMLQQ ILLRPAEYDV 

       310        320        330        340        350        360 
IATLNLNGDY LSDALAAEVG GIGIAPGANL SDSVAMFEAT HGTAPKYAGQ DKVNPGSLIL 

       370        380        390        400        410 
SAEMMLRHMG WTEAADLIIK GTNGAIAAKT VTYDFERLMD GATLLSCSEF GDAMIAKM 

« Hide

References

[1]Dodson R.J., Harkins D., Paulsen I.T.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PA7 EMBL ABR82501.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000744 Genomic DNA. Translation: ABR82501.1.
RefSeqYP_001347948.1. NC_009656.1.

3D structure databases

ProteinModelPortalA6V4G3.
SMRA6V4G3. Positions 5-418.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING381754.PSPA7_2584.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR82501; ABR82501; PSPA7_2584.
GeneID5356208.
KEGGpap:PSPA7_2584.
PATRIC19826915. VBIPseAer80442_2475.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
OrthoDBEOG6SNDTP.
ProtClustDBCLSK867410.

Enzyme and pathway databases

BioCycPAER381754:GHMY-2584-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6V4G3_PSEA7
AccessionPrimary (citable) accession number: A6V4G3
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: November 13, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)