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Protein

Alginate lyase

Gene

algL

Organism
Pseudomonas aeruginosa (strain PA7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond.UniRule annotation

Catalytic activityi

Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their non-reducing ends.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciPAER381754:GHMY-1598-MONOMER.

Protein family/group databases

CAZyiPL5. Polysaccharide Lyase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Alginate lyaseUniRule annotation (EC:4.2.2.3UniRule annotation)
Alternative name(s):
Poly(beta-D-mannuronate) lyaseUniRule annotation
Poly(mana) alginate lyaseUniRule annotation
Gene namesi
Name:algLUniRule annotation
Ordered Locus Names:PSPA7_1598
OrganismiPseudomonas aeruginosa (strain PA7)
Taxonomic identifieri381754 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000001582 Componenti: Chromosome

Subcellular locationi

  • Periplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727UniRule annotationAdd
BLAST
Chaini28 – 367340Alginate lyasePRO_1000061109Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi381754.PSPA7_1598.

Family & Domainsi

Sequence similaritiesi

Belongs to the polysaccharide lyase 5 family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG42597.
HOGENOMiHOG000247392.
KOiK01729.
OMAiAAWSVMA.
OrthoDBiEOG6H1PXF.

Family and domain databases

Gene3Di1.50.10.110. 1 hit.
HAMAPiMF_00557. Alginate_lyase.
InterProiIPR022859. Alginate_lyase.
IPR008397. Alginate_lyase_dom.
IPR008929. Chondroitin_lyas.
[Graphical view]
PfamiPF05426. Alginate_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF48230. SSF48230. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6V1P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTSHLIRIT LPGALAAALL ASQVSQAADL VPPPGYYAAV GERKGSAGSC
60 70 80 90 100
PSVPPPYTGS LVFTSKYEGS DSARATLNAK AEKAFRSQIK DITDMERGAT
110 120 130 140 150
KLVTQYMRSG RDGDLVCALN WMSAWARAGA LQSDDFNHTG KSMRKWALGS
160 170 180 190 200
LSGAYMRLKF SSSRPLSAHA GQSREIEDWF ARLGTQVVRD WSNLPLKKIN
210 220 230 240 250
NHSYWAAWSV MSTAVVTNRR DLFDWAVSEF KVAANQVDEQ GFLPNELKRR
260 270 280 290 300
QRALAYHNYA LPPLAMIAAF AQVNGVDLRQ ENHGALQRLA ERVMNGVDDE
310 320 330 340 350
ETFEEKTGED QDMTDLKVDN KYAWLEPYCA LYRCAPKMLE AKKDREPFNS
360
FRLGGEVTRV FSREGGS
Length:367
Mass (Da):40,774
Last modified:August 21, 2007 - v1
Checksum:i35ADE8EA39809C48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000744 Genomic DNA. Translation: ABR80788.1.
RefSeqiWP_012074764.1. NC_009656.1.
YP_001346982.1. NC_009656.1.

Genome annotation databases

EnsemblBacteriaiABR80788; ABR80788; PSPA7_1598.
KEGGipap:PSPA7_1598.
PATRICi19825005. VBIPseAer80442_1539.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000744 Genomic DNA. Translation: ABR80788.1.
RefSeqiWP_012074764.1. NC_009656.1.
YP_001346982.1. NC_009656.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi381754.PSPA7_1598.

Protein family/group databases

CAZyiPL5. Polysaccharide Lyase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR80788; ABR80788; PSPA7_1598.
KEGGipap:PSPA7_1598.
PATRICi19825005. VBIPseAer80442_1539.

Phylogenomic databases

eggNOGiNOG42597.
HOGENOMiHOG000247392.
KOiK01729.
OMAiAAWSVMA.
OrthoDBiEOG6H1PXF.

Enzyme and pathway databases

BioCyciPAER381754:GHMY-1598-MONOMER.

Family and domain databases

Gene3Di1.50.10.110. 1 hit.
HAMAPiMF_00557. Alginate_lyase.
InterProiIPR022859. Alginate_lyase.
IPR008397. Alginate_lyase_dom.
IPR008929. Chondroitin_lyas.
[Graphical view]
PfamiPF05426. Alginate_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF48230. SSF48230. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Dodson R.J., Harkins D., Paulsen I.T.
    Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PA7.

Entry informationi

Entry nameiALGL_PSEA7
AccessioniPrimary (citable) accession number: A6V1P7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: May 27, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.