A6UWU6 (RNP1_META3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 1
Short name=RNase P component 1
EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	Maeo_1392

Organism

Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280) [Complete proteome] [HAMAP]

Taxonomic identifier

419665 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	96 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00754
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 96	96	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_1000046612

Sequences

	Sequence		Length	Mass (Da)
	A6UWU6 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: B908A8A108419B74	FASTA	96	11,299
	10 20 30 40 50 60 MITPYNILRH ELIGLDVEIT QSTNKSLVGL KGKIVYETRN TINIERFDNS KEVMIPKDIA 70 80 90 VFKFKLNEEY IEVIGELLMG RPEDRLKRKI KNIYPY

References

[1]

"Complete sequence of Methanococcus aeolicus Nankai-3." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. , Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nankai-3 / ATCC BAA-1280.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000743 Genomic DNA. Translation: ABR56968.1.
RefSeq	YP_001325580.1. NC_009635.1.
3D structure databases
ProteinModelPortal	A6UWU6.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UWU6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5326403.
GenomeReviews	Gene locus Maeo_1392 in contig CP000743_GR.
KEGG	mae:Maeo_1392.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG12604.
HOGENOM	HBG704950.
OMA	ISTKGRV.
ProtClustDB	PRK03879.
Enzyme and pathway databases
BioCyc	MAEO419665:MAEO_1392-MONOMER.
Family and domain databases
HAMAP	MF_00754. RNase_P_1. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29. IPR023538. RNase_P_comp-1. IPR023534. Rof/RNase_P-like. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
KO	K03538.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
SUPFAM	SSF101744. RNase_P_Rpp29. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP1_META3

Accession

Primary (citable) accession number: A6UWU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program