Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A6UW60

- TF2B_META3

UniProt

A6UW60 - TF2B_META3

Protein

Transcription initiation factor IIB

Gene

tfb

Organism
Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi38 – 381ZincUniRule annotation
    Metal bindingi41 – 411ZincUniRule annotation
    Metal bindingi57 – 571ZincUniRule annotation
    Metal bindingi60 – 601ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri34 – 6532TFIIB-typeUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP
    2. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciMAEO419665:GHVZ-1178-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription initiation factor IIBUniRule annotation
    Short name:
    TFIIBUniRule annotation
    Gene namesi
    Name:tfbUniRule annotation
    Ordered Locus Names:Maeo_1155
    OrganismiMethanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
    Taxonomic identifieri419665 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
    ProteomesiUP000001106: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 334334Transcription initiation factor IIBPRO_1000080106Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi419665.Maeo_1155.

    Structurei

    3D structure databases

    ProteinModelPortaliA6UW60.
    SMRiA6UW60. Positions 138-334.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati151 – 234841Add
    BLAST
    Repeati245 – 326822Add
    BLAST

    Sequence similaritiesi

    Belongs to the TFIIB family.UniRule annotation
    Contains 1 TFIIB-type zinc finger.UniRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri34 – 6532TFIIB-typeUniRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG1405.
    HOGENOMiHOG000108633.
    KOiK03124.
    OMAiWRAFDHD.

    Family and domain databases

    Gene3Di1.10.472.10. 2 hits.
    HAMAPiMF_00383. TF2B_arch.
    InterProiIPR013763. Cyclin-like.
    IPR000812. TFIIB.
    IPR023484. TFIIB_arc.
    IPR023486. TFIIB_CS.
    IPR013150. TFIIB_cyclin.
    IPR013137. Znf_TFIIB.
    [Graphical view]
    PANTHERiPTHR11618. PTHR11618. 1 hit.
    PfamiPF08271. TF_Zn_Ribbon. 1 hit.
    PF00382. TFIIB. 2 hits.
    [Graphical view]
    PRINTSiPR00685. TIFACTORIIB.
    SMARTiSM00385. CYCLIN. 2 hits.
    [Graphical view]
    SUPFAMiSSF47954. SSF47954. 2 hits.
    PROSITEiPS00782. TFIIB. 2 hits.
    PS51134. ZF_TFIIB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6UW60-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDIKLISKKK NIEERKQLLS ELHASKSVIV EKDEELVCPM CDSKNIIKDY    50
    EKAEIVCEDC GCVLQDNLFD VGPEWRAFDH EQRVKRSRVG APMTYTIHDK 100
    GLSTVIDWRN KDSYGKDISA DKRAQLYRLR KWQRRIRVSD ASERNLAFAL 150
    SELDRIASKL GLPRNVRENA AVLYRGAVEK GLIRGRSIEG VAAAALYAAC 200
    RRCKVPRTLD EIAEMSRVDR KEIGRTYRFI SRELKIRLAP TSPIDYVPRF 250
    ASELKLPGEV ESKAISILQK AGDKGLTSGR GPTGVAAAAI YIASVLHGTR 300
    KTQREVADVA GVTEVTIRNR YKELTEHLDI DVTL 334
    Length:334
    Mass (Da):37,654
    Last modified:August 21, 2007 - v1
    Checksum:iA1609C576A679B6E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000743 Genomic DNA. Translation: ABR56732.1.
    RefSeqiYP_001325344.1. NC_009635.1.

    Genome annotation databases

    EnsemblBacteriaiABR56732; ABR56732; Maeo_1155.
    GeneIDi5327478.
    KEGGimae:Maeo_1155.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000743 Genomic DNA. Translation: ABR56732.1 .
    RefSeqi YP_001325344.1. NC_009635.1.

    3D structure databases

    ProteinModelPortali A6UW60.
    SMRi A6UW60. Positions 138-334.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 419665.Maeo_1155.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR56732 ; ABR56732 ; Maeo_1155 .
    GeneIDi 5327478.
    KEGGi mae:Maeo_1155.

    Phylogenomic databases

    eggNOGi COG1405.
    HOGENOMi HOG000108633.
    KOi K03124.
    OMAi WRAFDHD.

    Enzyme and pathway databases

    BioCyci MAEO419665:GHVZ-1178-MONOMER.

    Family and domain databases

    Gene3Di 1.10.472.10. 2 hits.
    HAMAPi MF_00383. TF2B_arch.
    InterProi IPR013763. Cyclin-like.
    IPR000812. TFIIB.
    IPR023484. TFIIB_arc.
    IPR023486. TFIIB_CS.
    IPR013150. TFIIB_cyclin.
    IPR013137. Znf_TFIIB.
    [Graphical view ]
    PANTHERi PTHR11618. PTHR11618. 1 hit.
    Pfami PF08271. TF_Zn_Ribbon. 1 hit.
    PF00382. TFIIB. 2 hits.
    [Graphical view ]
    PRINTSi PR00685. TIFACTORIIB.
    SMARTi SM00385. CYCLIN. 2 hits.
    [Graphical view ]
    SUPFAMi SSF47954. SSF47954. 2 hits.
    PROSITEi PS00782. TFIIB. 2 hits.
    PS51134. ZF_TFIIB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nankai-3 / ATCC BAA-1280.

    Entry informationi

    Entry nameiTF2B_META3
    AccessioniPrimary (citable) accession number: A6UW60
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3