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A6UW07 (SYR_META3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Maeo_1102
OrganismMethanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280) [Complete proteome] [HAMAP]
Taxonomic identifier419665 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length574 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 574574Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018058

Regions

Motif124 – 13411"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A6UW07 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: B57208CC9DB57A27

FASTA57465,551
        10         20         30         40         50         60 
MEQNITNILI KKIEELTETI YDETIRLEEP PSISLGDYST NISFKLAKLL KKSPMVIAEE 

        70         80         90        100        110        120 
LTNLLISENI EGIKEIKAVN GYINFFIDYN LYSKSGIAKI SSEKDKFGQG APKNKKVIIE 

       130        140        150        160        170        180 
HTSANPNGPL HIGHSRNAIV GDSLKRIVEF AGYVVEAQYY VNDMGRQEAI VVYGLDKFEL 

       190        200        210        220        230        240 
NEQQKPDHAI GEVYFKANQL LNENPEQEEE ILKLMKKYEE ASEKGEENEL TNKFNYAVNY 

       250        260        270        280        290        300 
ALSGFKETLN NLNIHHDKFV WESSYVKNGM VQKVIQTLKD TGKVEKDEVY RLDLSEFGID 

       310        320        330        340        350        360 
KKLVLARLNG TSLYSTRDIA YHIDKMKNCD IGINILGADH KLTAEMVNAS LKLLGYNTPE 

       370        380        390        400        410        420 
VVFYEFISLP EGSMSTRRGT FISIDELYEE AKNRAVKEIK KRNETTEEEE INNIAHKIAV 

       430        440        450        460        470        480 
GAVRYNIVRI SPDKAMVFRW DDALDFEKVG APVIQYAHAR CCRILEKENT NENKPIDATE 

       490        500        510        520        530        540 
LFEYDLNEHE KLLIKILLKF PKIVEKSADA KKPQIMATYA LDVAQTFNRY YANCPIFKEE 

       550        560        570 
NKNIVYSRLE LVKCTKTIIE NALNLLGIEC PGKM 

« Hide

References

[1]"Complete sequence of Methanococcus aeolicus Nankai-3."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nankai-3 / ATCC BAA-1280.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000743 Genomic DNA. Translation: ABR56679.1.
RefSeqYP_001325291.1. NC_009635.1.

3D structure databases

ProteinModelPortalA6UW07.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING419665.Maeo_1102.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR56679; ABR56679; Maeo_1102.
GeneID5327152.
KEGGmae:Maeo_1102.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMANFERNSA.

Enzyme and pathway databases

BioCycMAEO419665:GHVZ-1120-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_META3
AccessionPrimary (citable) accession number: A6UW07
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries