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A6UW07

- SYR_META3

UniProt

A6UW07 - SYR_META3

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Protein

Arginine--tRNA ligase

Gene
argS, Maeo_1102
Organism
Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMAEO419665:GHVZ-1120-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:Maeo_1102
OrganismiMethanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
Taxonomic identifieri419665 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000001106: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 574574Arginine--tRNA ligaseUniRule annotationPRO_1000018058Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi419665.Maeo_1102.

Structurei

3D structure databases

ProteinModelPortaliA6UW07.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi124 – 13411"HIGH" regionUniRule annotationAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247213.
KOiK01887.
OMAiNFERNSA.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6UW07-1 [UniParc]FASTAAdd to Basket

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MEQNITNILI KKIEELTETI YDETIRLEEP PSISLGDYST NISFKLAKLL    50
KKSPMVIAEE LTNLLISENI EGIKEIKAVN GYINFFIDYN LYSKSGIAKI 100
SSEKDKFGQG APKNKKVIIE HTSANPNGPL HIGHSRNAIV GDSLKRIVEF 150
AGYVVEAQYY VNDMGRQEAI VVYGLDKFEL NEQQKPDHAI GEVYFKANQL 200
LNENPEQEEE ILKLMKKYEE ASEKGEENEL TNKFNYAVNY ALSGFKETLN 250
NLNIHHDKFV WESSYVKNGM VQKVIQTLKD TGKVEKDEVY RLDLSEFGID 300
KKLVLARLNG TSLYSTRDIA YHIDKMKNCD IGINILGADH KLTAEMVNAS 350
LKLLGYNTPE VVFYEFISLP EGSMSTRRGT FISIDELYEE AKNRAVKEIK 400
KRNETTEEEE INNIAHKIAV GAVRYNIVRI SPDKAMVFRW DDALDFEKVG 450
APVIQYAHAR CCRILEKENT NENKPIDATE LFEYDLNEHE KLLIKILLKF 500
PKIVEKSADA KKPQIMATYA LDVAQTFNRY YANCPIFKEE NKNIVYSRLE 550
LVKCTKTIIE NALNLLGIEC PGKM 574
Length:574
Mass (Da):65,551
Last modified:August 21, 2007 - v1
Checksum:iB57208CC9DB57A27
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000743 Genomic DNA. Translation: ABR56679.1.
RefSeqiWP_011973811.1. NC_009635.1.
YP_001325291.1. NC_009635.1.

Genome annotation databases

EnsemblBacteriaiABR56679; ABR56679; Maeo_1102.
GeneIDi5327152.
KEGGimae:Maeo_1102.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000743 Genomic DNA. Translation: ABR56679.1 .
RefSeqi WP_011973811.1. NC_009635.1.
YP_001325291.1. NC_009635.1.

3D structure databases

ProteinModelPortali A6UW07.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 419665.Maeo_1102.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR56679 ; ABR56679 ; Maeo_1102 .
GeneIDi 5327152.
KEGGi mae:Maeo_1102.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247213.
KOi K01887.
OMAi NFERNSA.

Enzyme and pathway databases

BioCyci MAEO419665:GHVZ-1120-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nankai-3 / ATCC BAA-1280.

Entry informationi

Entry nameiSYR_META3
AccessioniPrimary (citable) accession number: A6UW07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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