A6UUZ8 (RPIA_META3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	Maeo_0737

Organism

Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280) [Complete proteome] [HAMAP]

Taxonomic identifier

419665 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 234	234	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_1000016947

Sequences

	Sequence		Length	Mass (Da)
	A6UUZ8 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 703BF9F34B6643D5	FASTA	234	25,364
	10 20 30 40 50 60 MARKKAVKVE ADPRLNAVNE ALKFIKDGMI VGLGSGTTAN LFIAELGKKI SEEGLNVFGV 70 80 90 100 110 120 PTSFESRMMA IQYGIPLVSL DEYGELDIAV DGADEVNKET LNVIKGGGGC HTQEKIIDYC 130 140 150 160 170 180 AKELIIIVDE SKLVDSLGEN TPVPLEVLPF AYSSVLNELL KMNSAPSIRM ADKKMGPVIT 190 200 210 220 230 DNGNMIIDVF IDLNNPEEVE KQLNNIPGVV ENGIFTKVDK VIVGKSDKAE ILKK

References

[1]

"Complete sequence of Methanococcus aeolicus Nankai-3." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. , Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nankai-3 / ATCC BAA-1280.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000743 Genomic DNA. Translation: ABR56320.1.
RefSeq	YP_001324932.1. NC_009635.1.
3D structure databases
ProteinModelPortal	A6UUZ8.
SMR	A6UUZ8. Positions 12-234.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UUZ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5327653.
GenomeReviews	Gene locus Maeo_0737 in contig CP000743_GR.
KEGG	mae:Maeo_0737.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG07879.
HOGENOM	HBG515603.
OMA	IPMAITP.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	MAEO419665:MAEO_0737-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_META3

Accession

Primary (citable) accession number: A6UUZ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program