Reviewed, UniProtKB/Swiss-Prot A6UUL7 (PDAD_META3)

Names and origin

Protein names

Recommended name:
    Pyruvoyl-dependent arginine decarboxylase
      Short name=PvlArgDC
    EC=4.1.1.19
Cleaved into the following 2 chains:
    1- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit beta
    2- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit alpha

Gene names

Name:	pdaD
Ordered Locus Names:	Maeo_0604

Organism

Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280) [Complete proteome] [HAMAP]

Taxonomic identifier

419665 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2. HAMAP MF_01404
Cofactor	Pyruvoyl group By similarity.
Sequence similarities	Belongs to the pdaD family.

Ontologies

Keywords
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 52	52	Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity		PRO_1000068391
	Chain	53 – 165	113	Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity		PRO_1000068392
Sites
	Site	52 – 53	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	53	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6UUL7-1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 3958CCEBEDBD8B43	FASTA	165	17,639
	10 20 30 40 50 60 MNDNISPIHS PYKAPNTISL VAGKGDTNNP LNAFDMALLD AGICNVNLIK ISSIMPPKAE 70 80 90 100 110 120 VVPLPDIPMG SLVPTAYGYK TSDIKGETVS AAVSVAIPKD KELCGLIMEY SAIGGKKETE 130 140 150 160 DTVREMAKTG FEMRGWEIDK IISLASECTV ENIGCAFAAV ALWYK

References

[1]

"Complete sequence of Methanococcus aeolicus Nankai-3." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. , Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000743 Genomic DNA. Translation: ABR56189.1.
RefSeq	YP_001324801.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A6UUL7.
Genome annotation databases
GeneID	5327655.
GenomeReviews	Gene locus Maeo_0604 in contig CP000743_GR.
KEGG	mae:Maeo_0604.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LVPTAYG.
Family and domain databases
HAMAP	MF_01404. [Tree]
InterPro	IPR016105. Pyr-dep_his/arg-deCO2ase_sand. IPR002724. Pyruvoyl-dep_arg_deCO2ase. [Graphical view]
Gene3D	G3DSA:3.50.20.10. Pyr-dep_his/arg-deCO2ase_sand. 1 hit.
Pfam	PF01862. PvlArgDC. 1 hit. [Graphical view]
PIRSF	PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDom	PD010449. DUF44. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00286. PvlArgDC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PDAD_META3

Accession

Primary (citable) accession number: A6UUL7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	August 21, 2007
Last modified:	November 3, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)