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A6UTQ9 (A6UTQ9_META3) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Amidophosphoribosyltransferase PIRNR PIRNR000485
Short name=ATase PIRNR PIRNR000485
EC=2.4.2.14 PIRNR PIRNR000485
Alternative name(s):
Glutamine phosphoribosylpyrophosphate amidotransferase PIRNR PIRNR000485
Gene names
Ordered Locus Names:Maeo_0292
OrganismMethanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280) [Complete proteome] [HAMAP] EMBL ABR55881.1
Taxonomic identifier419665 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length459 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O. PIRNR PIRNR000485

Cofactor

Binds 1 4Fe-4S cluster per subunit By similarity. PIRSR PIRSR000485-3

Binds 1 magnesium ion per subunit By similarity. PIRNR PIRNR000485

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. PIRNR PIRNR000485

Sequence similarities

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. PIRNR PIRNR000485

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site21For GATase activity By similarity PIRSR PIRSR000485-1
Metal binding2441Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding3901Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4391Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4421Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3

Sequences

Sequence LengthMass (Da)Tools
A6UTQ9 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: C4F0F6B98D23F424

FASTA45950,396
        10         20         30         40         50         60 
MCGIFGIYSF LNNDVASKIY YGLYALQHRG QEGSGIATFD GEKINSYKGL GLVPEIYTNE 

        70         80         90        100        110        120 
ILSELHGSVG IGHVRYSTTG DSCIENCQPF VVSSSIGSLS IVHNGDIVNS DKLKIELEKL 

       130        140        150        160        170        180 
GHIFMSSTDS EVIAHLLVRE LLKTDDIVEA VTNISKELIG SYAIIIMHNN KLIAVRGPNG 

       190        200        210        220        230        240 
FKPLCVGKDE DGSLYVSSES CGLDVINAKL IRDVKPGEII VIDGNGMESY NMMPENEKPV 

       250        260        270        280        290        300 
PSSCMFEYVY FARPDSIIDG VNVYDVRRNI GKILAKEHPC DADIVVPVPD SGITSAMGYS 

       310        320        330        340        350        360 
EEANIPYYEG LIKNRYVGRT FIIPSQEARV LAVRLKLNPI KHLIKDKKVV LIDDSIVRGT 

       370        380        390        400        410        420 
TSQRLIDLVR KAGAKEVHLR VGSPKIISPC FYGIDMPTKE ELIGSSKTVE EIREHITADS 

       430        440        450 
LGYLSIKGLI KAIGRKDLCF ACLTGNYPTE VSNKLNNVK

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References

[1]"Complete sequence of Methanococcus aeolicus Nankai-3."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nankai-3 / ATCC BAA-1280.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000743 Genomic DNA. Translation: ABR55881.1.
RefSeqYP_001324493.1. NC_009635.1.

3D structure databases

ProteinModelPortalA6UTQ9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6UTQ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5326606.
GenomeReviewsGene locus Maeo_0292 in contig CP000743_GR.
KEGGmae:Maeo_0292.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04070.
HOGENOMHBG392416.
OMADIAQMIC.
ProtClustDBCLSK876109.

Family and domain databases

InterProIPR005854. Amd_phspho_trans.
IPR000583. GATase_2.
IPR017932. GATase_II.
IPR000836. PRibTrfase.
[Graphical view]
KOK00764.
PANTHERPTHR11907. Amd_phspho_trans. 1 hit.
PfamPF00310. GATase_2. 1 hit.
PF00156. Pribosyltran. 1 hit.
[Graphical view]
PIRSFPIRSF000485. Amd_phspho_trans. 1 hit.
TIGRFAMsTIGR01134. PurF. 1 hit.
PROSITEPS51278. GATASE_TYPE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6UTQ9_META3
AccessionPrimary (citable) accession number: A6UTQ9
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info