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A6UTG8

- FUCA_META3

UniProt

A6UTG8 - FUCA_META3

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Protein

L-fuculose phosphate aldolase

Gene

fucA

Organism
Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the reversible aldol cleavage of L-fuculose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.By similarity

Catalytic activityi

L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.

Cofactori

Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi69 – 691ZincBy similarity
Metal bindingi88 – 881ZincBy similarity
Metal bindingi90 – 901ZincBy similarity
Metal bindingi148 – 1481ZincBy similarity

GO - Molecular functioni

  1. L-fuculose-phosphate aldolase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. fucose catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciMAEO419665:GHVZ-199-MONOMER.
UniPathwayiUPA00071.
UPA00563; UER00626.

Names & Taxonomyi

Protein namesi
Recommended name:
L-fuculose phosphate aldolase (EC:4.1.2.17)
Alternative name(s):
L-fuculose-1-phosphate aldolase
Gene namesi
Name:fucA
Ordered Locus Names:Maeo_0198
OrganismiMethanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
Taxonomic identifieri419665 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000001106: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 180180L-fuculose phosphate aldolasePRO_0000342594Add
BLAST

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi419665.Maeo_0198.

Structurei

3D structure databases

ProteinModelPortaliA6UTG8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0235.
HOGENOMiHOG000218182.
KOiK01628.
OMAiKPGTWEL.

Family and domain databases

Gene3Di3.40.225.10. 1 hit.
InterProiIPR001303. Aldolase_II/adducin_N.
[Graphical view]
PfamiPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTiSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMiSSF53639. SSF53639. 1 hit.

Sequencei

Sequence statusi: Complete.

A6UTG8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDNLKEFIKI CHYLYDRKYV VGSGGNVSIK KDNLIYVTPT DSLLGFINEE
60 70 80 90 100
DIAVVDMDGN IIKGAPTSEL YMHLNIYKKR NGVNAIVHTH SLYSTALPMA
110 120 130 140 150
DKEIKLLTPE SRIFLKKIGY VDYFEARSME LANEVSKKDE DVIVLKNHGI
160 170 180
VCVGKNLMDA YLKTEVMEEI SQLNYIIHSL
Length:180
Mass (Da):20,464
Last modified:August 21, 2007 - v1
Checksum:i2A0EAE2305C9839E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000743 Genomic DNA. Translation: ABR55790.1.
RefSeqiYP_001324402.1. NC_009635.1.

Genome annotation databases

EnsemblBacteriaiABR55790; ABR55790; Maeo_0198.
GeneIDi5326583.
KEGGimae:Maeo_0198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000743 Genomic DNA. Translation: ABR55790.1 .
RefSeqi YP_001324402.1. NC_009635.1.

3D structure databases

ProteinModelPortali A6UTG8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 419665.Maeo_0198.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR55790 ; ABR55790 ; Maeo_0198 .
GeneIDi 5326583.
KEGGi mae:Maeo_0198.

Phylogenomic databases

eggNOGi COG0235.
HOGENOMi HOG000218182.
KOi K01628.
OMAi KPGTWEL.

Enzyme and pathway databases

UniPathwayi UPA00071 .
UPA00563 ; UER00626 .
BioCyci MAEO419665:GHVZ-199-MONOMER.

Family and domain databases

Gene3Di 3.40.225.10. 1 hit.
InterProi IPR001303. Aldolase_II/adducin_N.
[Graphical view ]
Pfami PF00596. Aldolase_II. 1 hit.
[Graphical view ]
SMARTi SM01007. Aldolase_II. 1 hit.
[Graphical view ]
SUPFAMi SSF53639. SSF53639. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nankai-3 / ATCC BAA-1280.

Entry informationi

Entry nameiFUCA_META3
AccessioniPrimary (citable) accession number: A6UTG8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: August 21, 2007
Last modified: November 26, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3