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A6UTG8

- FUCA_META3

UniProt

A6UTG8 - FUCA_META3

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Protein
L-fuculose phosphate aldolase
Gene
fucA, Maeo_0198
Organism
Methanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the reversible aldol cleavage of L-fuculose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde By similarity.

Catalytic activityi

L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.

Cofactori

Binds 1 zinc ion per subunit Reviewed prediction.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi69 – 691Zinc By similarity
Metal bindingi88 – 881Zinc By similarity
Metal bindingi90 – 901Zinc By similarity
Metal bindingi148 – 1481Zinc By similarity

GO - Molecular functioni

  1. L-fuculose-phosphate aldolase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. fucose catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciMAEO419665:GHVZ-199-MONOMER.
UniPathwayiUPA00071.
UPA00563; UER00626.

Names & Taxonomyi

Protein namesi
Recommended name:
L-fuculose phosphate aldolase (EC:4.1.2.17)
Alternative name(s):
L-fuculose-1-phosphate aldolase
Gene namesi
Name:fucA
Ordered Locus Names:Maeo_0198
OrganismiMethanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280)
Taxonomic identifieri419665 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000001106: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 180180L-fuculose phosphate aldolase
PRO_0000342594Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.

Protein-protein interaction databases

STRINGi419665.Maeo_0198.

Structurei

3D structure databases

ProteinModelPortaliA6UTG8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0235.
HOGENOMiHOG000218182.
KOiK01628.
OMAiKPGTWEL.

Family and domain databases

Gene3Di3.40.225.10. 1 hit.
InterProiIPR001303. Aldolase_II/adducin_N.
[Graphical view]
PfamiPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTiSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMiSSF53639. SSF53639. 1 hit.

Sequencei

Sequence statusi: Complete.

A6UTG8-1 [UniParc]FASTAAdd to Basket

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MDNLKEFIKI CHYLYDRKYV VGSGGNVSIK KDNLIYVTPT DSLLGFINEE    50
DIAVVDMDGN IIKGAPTSEL YMHLNIYKKR NGVNAIVHTH SLYSTALPMA 100
DKEIKLLTPE SRIFLKKIGY VDYFEARSME LANEVSKKDE DVIVLKNHGI 150
VCVGKNLMDA YLKTEVMEEI SQLNYIIHSL 180
Length:180
Mass (Da):20,464
Last modified:August 21, 2007 - v1
Checksum:i2A0EAE2305C9839E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000743 Genomic DNA. Translation: ABR55790.1.
RefSeqiWP_011972922.1. NC_009635.1.
YP_001324402.1. NC_009635.1.

Genome annotation databases

EnsemblBacteriaiABR55790; ABR55790; Maeo_0198.
GeneIDi5326583.
KEGGimae:Maeo_0198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000743 Genomic DNA. Translation: ABR55790.1 .
RefSeqi WP_011972922.1. NC_009635.1.
YP_001324402.1. NC_009635.1.

3D structure databases

ProteinModelPortali A6UTG8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 419665.Maeo_0198.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR55790 ; ABR55790 ; Maeo_0198 .
GeneIDi 5326583.
KEGGi mae:Maeo_0198.

Phylogenomic databases

eggNOGi COG0235.
HOGENOMi HOG000218182.
KOi K01628.
OMAi KPGTWEL.

Enzyme and pathway databases

UniPathwayi UPA00071 .
UPA00563 ; UER00626 .
BioCyci MAEO419665:GHVZ-199-MONOMER.

Family and domain databases

Gene3Di 3.40.225.10. 1 hit.
InterProi IPR001303. Aldolase_II/adducin_N.
[Graphical view ]
Pfami PF00596. Aldolase_II. 1 hit.
[Graphical view ]
SMARTi SM01007. Aldolase_II. 1 hit.
[Graphical view ]
SUPFAMi SSF53639. SSF53639. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nankai-3 / ATCC BAA-1280.

Entry informationi

Entry nameiFUCA_META3
AccessioniPrimary (citable) accession number: A6UTG8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: August 21, 2007
Last modified: September 3, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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