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A6UTB9 (AROA_META3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Maeo_0149
OrganismMethanococcus aeolicus (strain Nankai-3 / ATCC BAA-1280) [Complete proteome] [HAMAP]
Taxonomic identifier419665 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length433 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 433433Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_0000325402

Sequences

Sequence LengthMass (Da)Tools
A6UTB9 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 5DB81D3BFE4622EF

FASTA43346,952
        10         20         30         40         50         60 
MIIIEKTEQI KGTINAPPSK SYTHRAVICA SLADGTSEII SPLNSADCLS SVHGAMMLGA 

        70         80         90        100        110        120 
EIDATDKNKW VVVGNNNSPK TPNNVVDIGN SGTTLRILTG IASQIPEGYA ILTGDSSIIT 

       130        140        150        160        170        180 
RPMQPLLDAL NQLGIRAFSS KTDGTAPIIV EHGEIKNNVV KIRGDMSSQF ITSLMMTMPF 

       190        200        210        220        230        240 
SKMDSTIELT TPLKSAPYLD ITIDVLDKFG VKIEKVKNKN KLTKFIIKGN QKYKPYSYTV 

       250        260        270        280        290        300 
EGDCSSASYF IAAGVLMNSD ITINNIFKNS KQGDREIVNI VKKMGAPIIE EEDKIIIKGP 

       310        320        330        340        350        360 
YKLKGIDIDV KDTPDLVPTI AILGCFAEGT TTIYNGEHVR LKECDRLMAC AKELTKMGAK 

       370        380        390        400        410        420 
ITEKPDGLII EGVGKLNGAE METYHDHRLV MAFTVAGMMA EGKTIIKGED AVKISFPNFV 

       430 
EAIKSIGANI TIK

« Hide

References

[1]"Complete sequence of Methanococcus aeolicus Nankai-3."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nankai-3 / ATCC BAA-1280.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000743 Genomic DNA. Translation: ABR55741.1.
RefSeqYP_001324353.1. NC_009635.1.

3D structure databases

ProteinModelPortalA6UTB9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6UTB9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5327505.
GenomeReviewsGene locus Maeo_0149 in contig CP000743_GR.
KEGGmae:Maeo_0149.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05032.
HOGENOMHBG646626.
OMANYTTRYL.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycMAEO419665:MAEO_0149-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_META3
AccessionPrimary (citable) accession number: A6UTB9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: August 21, 2007
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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