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A6URL2 (GSA_METVS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate-1-semialdehyde 2,1-aminomutase

Short name=GSA
EC=5.4.3.8
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name=GSA-AT
Gene names
Name:hemL
Ordered Locus Names:Mevan_1237
OrganismMethanococcus vannielii (strain SB / ATCC 35089 / DSM 1224) [Complete proteome] [HAMAP]
Taxonomic identifier406327 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   LigandPyridoxal phosphate
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotoporphyrinogen IX biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglutamate-1-semialdehyde 2,1-aminomutase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

transaminase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Glutamate-1-semialdehyde 2,1-aminomutase HAMAP-Rule MF_00375
PRO_0000382403

Amino acid modifications

Modified residue2681N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
A6URL2 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 875A8481563A41AA

FASTA42747,198
        10         20         30         40         50         60 
MDLNIKLDKS GELFNESKKY LVGGVNSPVR SFKPFPFFVK SAKSCFLYDE DGNEFIDYCL 

        70         80         90        100        110        120 
AYGPMVLGHA NEKILNAVKE QMDFGTAYGV PSEKEIILAK EVINRIPCAE MVRFVNSGTE 

       130        140        150        160        170        180 
ATMGAIRLAR GVTKRNKIIK FEGAFHGAHD YVLVKSGSGA LTHGAPNSPG IPEDTTKNTL 

       190        200        210        220        230        240 
LIPFNDEGAV RKVISENKGE IACIILEPMM GNVGCILPKD GYLKFLREIT EENGIILIFD 

       250        260        270        280        290        300 
EVITGFRLSK GGAQEYYGVK ADIATLGKIL GGGFPIGAIA GKKELMEQFS PKGQVYQAGT 

       310        320        330        340        350        360 
FNGNPISVTA GIETLKNLNN AFYKETAKKA EILSNYLIET TEKYKIPARV YSVASIFQVY 

       370        380        390        400        410        420 
FNDKDILTYD DAKSSDTEKF MKYFYSLLEN GVFIPPSQFE CCFTSIKHDD FVLEKTMNAI 


DIAMKKL 

« Hide

References

[1]"Complete sequence of Methanococcus vannielii SB."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. expand/collapse author list , Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SB / ATCC 35089 / DSM 1224.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000742 Genomic DNA. Translation: ABR55134.1.
RefSeqYP_001323746.1. NC_009634.1.

3D structure databases

ProteinModelPortalA6URL2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING406327.Mevan_1237.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR55134; ABR55134; Mevan_1237.
GeneID5324909.
KEGGmvn:Mevan_1237.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0001.
HOGENOMHOG000020210.
KOK01845.
OMARAIKPYP.

Enzyme and pathway databases

BioCycMVAN406327:GI04-1281-MONOMER.
UniPathwayUPA00251; UER00317.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPMF_00375. HemL_aminotrans_3.
InterProIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR00713. hemL. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSA_METVS
AccessionPrimary (citable) accession number: A6URL2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: August 21, 2007
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways