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Reviewed, UniProtKB/Swiss-Prot A6URG2 (RIFK_METVS)

Last modified November 3, 2009. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Riboflavin kinase
      Short name=RFK
    EC=2.7.1.161
Alternative name(s):
    CTP:riboflavin 5'-phosphotransferase
    CTP-dependent riboflavin kinase
    Flavokinase
Gene names
Name: rfk
Ordered Locus Names: Mevan_1186
OrganismMethanococcus vannielii (strain SB / ATCC 35089 / DSM 1224) [Complete proteome] [HAMAP]
Taxonomic identifier406327 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length130 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) By similarity.

Catalytic activity

CTP + riboflavin = CDP + FMN. HAMAP MF_01285

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Pathway

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (CTP route): step 1/1. HAMAP MF_01285

Sequence similarities

Belongs to the archaeal riboflavin kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 130130Riboflavin kinase HAMAP MF_01285
PRO_0000322074

Regions

Nucleotide binding10 – 156CDP By similarity
Nucleotide binding109 – 1124CDP By similarity

Sites

Metal binding391Magnesium By similarity
Metal binding411Magnesium By similarity
Binding site961FMN By similarity
Binding site1041FMN By similarity

Sequences

Sequence LengthMass (Da)Tools
A6URG2-1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: C7FF82C7DD6E5DEF

FASTA13014,781
        10         20         30         40         50         60 
MKIFGRVVSG FGEGKYFVGL IPYKNKFKEL TGFTPYEGTL NIKLKTYFDI DKYDPLEFDG 

        70         80         90        100        110        120 
FEIDGKEYFG GKVLLVTLFN KSGKFVDCAI VSPKKTDHSK KTLEIIAPVN LRKFLSLKNL 

       130 
DIVKIIQALK 

« Hide

References

[1]"Complete sequence of Methanococcus vannielii SB."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. expand/collapse author list , Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000742 Genomic DNA. Translation: ABR55084.1.
RefSeqYP_001323696.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA6URG2.

Genome annotation databases

GeneID5325344.
GenomeReviewsGene locus Mevan_1186 in contig CP000742_GR.
KEGGmvn:Mevan_1186.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAKTDHSKK.

Family and domain databases

HAMAPMF_01285.
[Tree]
InterProIPR002834. Riboflavin_kinase_arc.
[Graphical view]
PfamPF01982. CTP-dep_RFKase. 1 hit.
[Graphical view]
ProDomPD015839. DUF120. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameRIFK_METVS
AccessionPrimary (citable) accession number: A6URG2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: November 3, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents