A6URG2 (RIFK_METVS) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 33.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Riboflavin kinase Short name=RFK EC=2.7.1.161 Alternative name(s): CTP-dependent riboflavin kinase CTP:riboflavin 5'-phosphotransferase Flavokinase | ||||
| Gene names |
| ||||
| Organism | Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 406327 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus |
Protein attributes
| Sequence length | 130 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) By similarity. HAMAP MF_01285 |
| Catalytic activity | CTP + riboflavin = CDP + FMN. HAMAP MF_01285 |
| Cofactor | Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01285 |
| Pathway | Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (CTP route): step 1/1. HAMAP MF_01285 |
| Sequence similarities | Belongs to the archaeal riboflavin kinase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | FMN Magnesium Metal-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | riboflavin biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Molecular function | metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide bindingInferred from electronic annotation. Source: UniProtKB-KW riboflavin kinase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 130 | 130 | Riboflavin kinase HAMAP MF_01285 | PRO_0000322074 | |||||
Regions | |||||||||
| Nucleotide binding | 10 – 15 | 6 | CDP By similarity | ||||||
| Nucleotide binding | 109 – 112 | 4 | CDP By similarity | ||||||
Sites | |||||||||
| Metal binding | 39 | 1 | Magnesium By similarity | ||||||
| Metal binding | 41 | 1 | Magnesium By similarity | ||||||
| Binding site | 96 | 1 | FMN By similarity | ||||||
| Binding site | 104 | 1 | FMN By similarity | ||||||
Sequences
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References
| [1] | "Complete sequence of Methanococcus vannielii SB." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. Richardson P.Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SB / ATCC 35089 / DSM 1224. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000742 Genomic DNA. Translation: ABR55084.1. |
| RefSeq | YP_001323696.1. NC_009634.1. |
3D structure databases | |
| ProteinModelPortal | A6URG2. |
| SMR | A6URG2. Positions 1-129. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A6URG2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 5325344. |
| GenomeReviews | Gene locus Mevan_1186 in contig CP000742_GR. |
| KEGG | mvn:Mevan_1186. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | arNOG11680. |
| HOGENOM | HBG553349. |
| OMA | PYEGTLN. |
| ProtClustDB | PRK14132. |
Family and domain databases | |
| HAMAP | MF_01285. Riboflavin_kinase. [Tree] |
| InterPro | IPR023470. Riboflavin_kinase_archaeal. IPR023602. Riboflavin_kinase_CTP-dep. IPR023465. Riboflavin_kinase_domain. [Graphical view] |
| Gene3D | G3DSA:2.40.30.30. Riboflavin_kinase. 1 hit. |
| KO | K07732. |
| Pfam | PF01982. CTP-dep_RFKase. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | RIFK_METVS | ||||||||
| Accession | Primary (citable) accession number: A6URG2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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