A6UQ84 (APGM_METVS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Mevan_0750

Organism

Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224) [Complete proteome] [HAMAP]

Taxonomic identifier

406327 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 406	406	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_1000087367

Sequences

	Sequence		Length	Mass (Da)
	A6UQ84 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 1C1C4BC8E2EF6FAB	FASTA	406	44,562
	10 20 30 40 50 60 MKAVIFVIDG LGDRPDEFGN TPLKEANTHT MDKIAKEGIC GIMNAIDIGV RPGSDTAHLA 70 80 90 100 110 120 LLGYDPYETY TGRGPFEACG VGITVKPGDI AFRCNFSSVD KEFIVTDRRA GRIEDTSLLE 130 140 150 160 170 180 KELDGLKIDD VEVIFKESGG YRAALLLRGP NLSDKISDAD PKKEGKKVKE IIPLDDSKEA 190 200 210 220 230 240 EKTANILNRL LKVAYEKLDG HPVNQKRRTN NLPVANMIIP RGVGKVPEII PFDKKYGLKG 250 260 270 280 290 300 ACIAGTGLIK GIAKMVNLDV IEVKGATGTP DSNFMAKAKA LVETLKTHDF VLINVKGADE 310 320 330 340 350 360 AGHDGNYEVK KQVIEKIDEM LTYIMENIDR KDVYFVLTGD HSTPIEEMDH SADPLPIVIW 370 380 390 400 GKSVRVDDVE KFDEFSTCKG GLNWIKGKNI MPILIDLMGL SKKYGA

References

[1]

"Complete sequence of Methanococcus vannielii SB." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. , Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SB / ATCC 35089 / DSM 1224.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000742 Genomic DNA. Translation: ABR54656.1.
RefSeq	YP_001323268.1. NC_009634.1.
3D structure databases
ProteinModelPortal	A6UQ84.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UQ84.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5325430.
GenomeReviews	Gene locus Mevan_0750 in contig CP000742_GR.
KEGG	mvn:Mevan_0750.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04733.
HOGENOM	HBG463247.
OMA	DIAFRCN.
ProtClustDB	PRK04024.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METVS

Accession

Primary (citable) accession number: A6UQ84

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program