A6UQ71 (DCD_METVS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Mevan_0737

Organism

Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224) [Complete proteome] [HAMAP]

Taxonomic identifier

406327 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 206	206	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000117985

Sequences

	Sequence		Length	Mass (Da)
	A6UQ71 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 64A2F96A8C3545B8	FASTA	206	23,572
	10 20 30 40 50 60 MILSDKDILN YVNSGRVCIN PFNRNFVGPC SYDVTLGEEF ITYNEDVYDV KKQLSHRSFK 70 80 90 100 110 120 IDNSIMVCPL HHHLDEKIIE RYKEKYSIDC VVSGGLLGTT NEYVELPNDV CAQYQGRSSF 130 140 150 160 170 180 GRVFLQSHQT AGWIDSGFKG KITLEIVAYD KPVILYKNQR IGQLIFSKTL SPADIGYSDR 190 200 KCSKYARQTS VMPSLIKKDF ENDLEE

References

[1]

"Complete sequence of Methanococcus vannielii SB." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. , Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SB / ATCC 35089 / DSM 1224.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000742 Genomic DNA. Translation: ABR54643.1.
RefSeq	YP_001323255.1. NC_009634.1.
3D structure databases
ProteinModelPortal	A6UQ71.
SMR	A6UQ71. Positions 1-199.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UQ71.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5325639.
GenomeReviews	Gene locus Mevan_0737 in contig CP000742_GR.
KEGG	mvn:Mevan_0737.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG05800.
HOGENOM	HBG553199.
OMA	HQTAGWI.
ProtClustDB	CLSK876187.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METVS

Accession

Primary (citable) accession number: A6UQ71

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program