A6UPV2 (TAL_METVS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	Mevan_0618

Organism

Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224) [Complete proteome] [HAMAP]

Taxonomic identifier

406327 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00494
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494
Subcellular location	Cytoplasm By similarity HAMAP MF_00494.
Sequence similarities	Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 215	215	Probable transaldolase HAMAP MF_00494		PRO_1000060473
Sites
	Active site	83	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6UPV2 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: CC189078CAE1D1C1	FASTA	215	23,460
	10 20 30 40 50 60 MKFFLDTANV EKIKEFNALG LVDGVTTNPS LIKKEGRDFY EVIKEICSIV KGPVSAEVIA 70 80 90 100 110 120 LDAEGMIKEA KELVKIAENV VIKIPMTKEG MKAVNILSKE GIKTNVTLIF SANQALLAAK 130 140 150 160 170 180 AGATYVSPFV GRLDDIGQDG LLLISEIMQI FSAYGIETEV IVASVRHPIH VTESAKMGAD 190 200 210 VATIPFDVLD KLFNHSLTDI GIEKFLADWD AHLKR

References

[1]

"Complete sequence of Methanococcus vannielii SB." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. , Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SB / ATCC 35089 / DSM 1224.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000742 Genomic DNA. Translation: ABR54524.1.
RefSeq	YP_001323136.1. NC_009634.1.
3D structure databases
ProteinModelPortal	A6UPV2.
SMR	A6UPV2. Positions 1-214.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UPV2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5325071.
GenomeReviews	Gene locus Mevan_0618 in contig CP000742_GR.
KEGG	mvn:Mevan_0618.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG05880.
HOGENOM	HBG533000.
OMA	KVNVTLC.
ProtClustDB	PRK01362.
Family and domain databases
HAMAP	MF_00494. Transaldolase_3b. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004731. Transaldolase_3A/3B. IPR022999. Transaldolase_3B. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00875. Fsa_talC_mipB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_METVS

Accession

Primary (citable) accession number: A6UPV2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program