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A6UP61 (SURE_METVS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
5'-nucleotidase surE
EC=3.1.3.5
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase
Gene names
Name:surE
Ordered Locus Names:Mevan_0374
OrganismMethanococcus vannielii (strain SB / ATCC 35089 / DSM 1224) [Complete proteome] [HAMAP]
Taxonomic identifier406327 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060

Catalytic activity

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060

Cofactor

Binds 1 divalent metal cation per subunit By similarity.

Subcellular location

Cytoplasm Potential HAMAP MF_00060.

Sequence similarities

Belongs to the surE nucleotidase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function5'-nucleotidase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

nucleotide binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2642645'-nucleotidase surE HAMAP MF_00060
PRO_0000335295

Sites

Metal binding101Divalent metal cation By similarity
Metal binding111Divalent metal cation By similarity
Metal binding431Divalent metal cation By similarity
Metal binding991Divalent metal cation By similarity

Sequences

Sequence LengthMass (Da)Tools
A6UP61 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: F8B61EAC72E40352

FASTA26429,271
        10         20         30         40         50         60 
MTLEILLVND DGIYSNGLLA LKNVLSSEFD ANVTVVAPTN QQSGIGRAIS FFEPLRITKT 

        70         80         90        100        110        120 
KLSDCSEGYA VSGTPSDCVV LGIYQVLKKV PDFVISGINI GENLGTEITT SGTLGAAFEG 

       130        140        150        160        170        180 
SHHGAKAFAC SLQVTADHLK FKEGESPIEF LNAANVFKKV FEKFLDSEFP CDVLNVNIPE 

       190        200        210        220        230        240 
DATLNTPVEI TKLAKKMYTT HVEERIDPRS RSYYWIDGYP IMEEEDGTDV YAIRRKKHVS 

       250        260 
LTPLTLDTTI KNIELFQEIY KKKF

« Hide

References

[1]"Complete sequence of Methanococcus vannielii SB."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. expand/collapse author list , Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SB / ATCC 35089 / DSM 1224.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000742 Genomic DNA. Translation: ABR54283.1.
RefSeqYP_001322895.1. NC_009634.1.

3D structure databases

ProteinModelPortalA6UP61.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6UP61.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5325750.
GenomeReviewsGene locus Mevan_0374 in contig CP000742_GR.
KEGGmvn:Mevan_0374.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05083.
HOGENOMHBG600532.
OMAPINIDMT.
ProtClustDBPRK00346.

Family and domain databases

HAMAPMF_00060. SurE.
[Tree]
InterProIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
Gene3DG3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KOK03787.
PfamPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMSSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMsTIGR00087. SurE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSURE_METVS
AccessionPrimary (citable) accession number: A6UP61
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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