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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMVAN406327:G1G99-365-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mevan_0350
OrganismiMethanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Taxonomic identifieri406327 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000001107 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180671 – 569Arginine--tRNA ligaseAdd BLAST569

Proteomic databases

PRIDEiA6UP37

Interactioni

Protein-protein interaction databases

STRINGi406327.Mevan_0350

Structurei

3D structure databases

ProteinModelPortaliA6UP37
SMRiA6UP37
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A6UP37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVKKLIVVA IEKKVLDLTG KQIEIRLDEP PSINMGDYST NIAFRLSKEL
60 70 80 90 100
KKAPKIIAEE ITSSLSIPGI EKIESLNGYI NFFMDYSVFS KETTLEINSK
110 120 130 140 150
QENFGKSDLK NKKVILEHTS ANPNGPFHIG HGRNMVIGDS LKRILNAAGY
160 170 180 190 200
TVETQYYVND MGRQEAIVVF GNDRFKLDKS KKSDHAIGQT YVEANKLLNE
210 220 230 240 250
NEELEQEILN LMKNYEEAME NGIENEITEK FKNAVEYALT GFKETLSTLN
260 270 280 290 300
IHHDKFVWES EFVRSGLVRN VINRLMETGK VTEEDVYRLD LSEFGIEKKL
310 320 330 340 350
VLARLNGTSL YSTRDVAYHM TKMENCDFAV NLLGADHKLT GIMVNKTLAL
360 370 380 390 400
LGYNEAEIVF YEFISLPEGS MSTRQGRFIS MDELFEEAKL RAREEVKKRE
410 420 430 440 450
VAKTEEEIEE IAKKIAVGAV RYNIVRISPE KPMVFRWDEA LDFEKVGCPV
460 470 480 490 500
IQYAHARCSR ILENCEPSGL VNSKNLFEYE MAENEKIIVK LISKLPEIVE
510 520 530 540 550
KSAEVRKPQI LANYALELAQ GFNKFYGNCR ILKEENETVR NSRIMIVNST
560
KLVLENSLDL LGIEMPGKM
Length:569
Mass (Da):64,914
Last modified:August 21, 2007 - v1
Checksum:i240BB70466A8A880
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000742 Genomic DNA Translation: ABR54259.1
RefSeqiWP_011972162.1, NC_009634.1

Genome annotation databases

EnsemblBacteriaiABR54259; ABR54259; Mevan_0350
GeneIDi5325871
KEGGimvn:Mevan_0350

Similar proteinsi

Entry informationi

Entry nameiSYR_METVS
AccessioniPrimary (citable) accession number: A6UP37
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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