A6UKY9 (A6UKY9_SINMW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 3 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 3 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 3 HAMAP MF_01401

Gene names

Name:	msrA3 HAMAP MF_01401
Ordered Locus Names:	Smed_5572

Encoded on

Plasmid pSMED02 EMBL ABR64319.1

Organism

Sinorhizobium medicae (strain WSM419) (Ensifer medicae) [Complete proteome] [HAMAP]

Taxonomic identifier

366394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ABR64319.1
Technical term	Complete proteome Plasmid EMBL ABR64319.1
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	11	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A6UKY9 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: B41B060C6E8C6E96	FASTA	168	19,147
	10 20 30 40 50 60 MTKRAVLAGG CFWGMQDLIR KLPGVIETRV GYTGGDVPNA TYRNHGTHAE GIEIIFDPER 70 80 90 100 110 120 ISYGRILELF FQIHDPTTKN RQGNDIGTSY RSAIYYVDDE QKRIAEETIA DVEASGLWPG 130 140 150 160 KVVTEVEPVG DFWEAEPEHQ DYLERYPNGY TCHFPRPDWV LPRRSAAE

References

[1]

"Complete sequence of Sinorhizobium medicae WSM419 plasmid pSMED02." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM419.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000740 Genomic DNA. Translation: ABR64319.1.
RefSeq	YP_001314252.1. NC_009621.1.
3D structure databases
ProteinModelPortal	A6UKY9.
SMR	A6UKY9. Positions 3-164.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UKY9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5319874.
GenomeReviews	Gene locus Smed_5572 in contig CP000740_GR.
KEGG	smd:Smed_5572.
PATRIC	23616804. VBISinMed134228_2072.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	YRQILEF.
ProtClustDB	PRK14054.
Enzyme and pathway databases
BioCyc	SMED366394:SMED_5572-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6UKY9_SINMW

Accession

Primary (citable) accession number: A6UKY9

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)