Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A6UEK2

- HIS2_SINMW

UniProt

A6UEK2 - HIS2_SINMW

Protein

Phosphoribosyl-ATP pyrophosphatase

Gene

hisE

Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Catalytic activityi

    1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-AMP + diphosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosyl-ATP diphosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. histidine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Amino-acid biosynthesis, Histidine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSMED366394:GJAL-3310-MONOMER.
    UniPathwayiUPA00031; UER00007.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosyl-ATP pyrophosphataseUniRule annotation (EC:3.6.1.31UniRule annotation)
    Short name:
    PRA-PHUniRule annotation
    Gene namesi
    Name:hisEUniRule annotation
    Ordered Locus Names:Smed_3258
    OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)
    Taxonomic identifieri366394 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
    ProteomesiUP000001108: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 107107Phosphoribosyl-ATP pyrophosphatasePRO_1000063384Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi366394.Smed_3258.

    Structurei

    3D structure databases

    ProteinModelPortaliA6UEK2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PRA-PH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0140.
    HOGENOMiHOG000220965.
    KOiK01523.
    OMAiPEKCAEK.
    OrthoDBiEOG6CGCMH.

    Family and domain databases

    HAMAPiMF_01020. HisE.
    InterProiIPR008179. PRib-ATP_PPHydrolase.
    IPR021130. PRib-ATP_PPHydrolase-like.
    [Graphical view]
    PfamiPF01503. PRA-PH. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03188. histidine_hisI. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6UEK2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTEFTLSDLE KIVATRARAA PEESWTAKLV AAGQKKAAKK LGEEAVETVI    50
    AAIGDDRKNL VDESADLLYH LMVVLNIAAI PLQDVMSELA RRTSQSGLQE 100
    KANRQNP 107
    Length:107
    Mass (Da):11,660
    Last modified:August 21, 2007 - v1
    Checksum:i0517AE382703FC91
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000738 Genomic DNA. Translation: ABR62082.1.
    RefSeqiYP_001328917.1. NC_009636.1.

    Genome annotation databases

    EnsemblBacteriaiABR62082; ABR62082; Smed_3258.
    GeneIDi5324137.
    KEGGismd:Smed_3258.
    PATRICi23625761. VBISinMed134228_6498.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000738 Genomic DNA. Translation: ABR62082.1 .
    RefSeqi YP_001328917.1. NC_009636.1.

    3D structure databases

    ProteinModelPortali A6UEK2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 366394.Smed_3258.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR62082 ; ABR62082 ; Smed_3258 .
    GeneIDi 5324137.
    KEGGi smd:Smed_3258.
    PATRICi 23625761. VBISinMed134228_6498.

    Phylogenomic databases

    eggNOGi COG0140.
    HOGENOMi HOG000220965.
    KOi K01523.
    OMAi PEKCAEK.
    OrthoDBi EOG6CGCMH.

    Enzyme and pathway databases

    UniPathwayi UPA00031 ; UER00007 .
    BioCyci SMED366394:GJAL-3310-MONOMER.

    Family and domain databases

    HAMAPi MF_01020. HisE.
    InterProi IPR008179. PRib-ATP_PPHydrolase.
    IPR021130. PRib-ATP_PPHydrolase-like.
    [Graphical view ]
    Pfami PF01503. PRA-PH. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03188. histidine_hisI. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Sinorhizobium medicae WSM419 chromosome."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P.
      Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WSM419.

    Entry informationi

    Entry nameiHIS2_SINMW
    AccessioniPrimary (citable) accession number: A6UEK2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3