A6UEE7 (RSMG_SINMW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	Smed_3203

Organism

Sinorhizobium medicae (strain WSM419) (Ensifer medicae) [Complete proteome] [HAMAP]

Taxonomic identifier

366394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanosine in position 527 of 16S rRNA By similarity. HAMAP MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanosine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanosine(527) in 16S rRNA. HAMAP MF_00074
Subcellular location	Cytoplasm Potential HAMAP MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	Ribosomal RNA small subunit methyltransferase G HAMAP MF_00074		PRO_1000010211

Sequences

	Sequence		Length	Mass (Da)
	A6UEE7 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 32E6AD7253E14C3B	FASTA	213	23,781
	10 20 30 40 50 60 MQTSLNRALN GLRVSRETVE KLEHFASLFQ KWARSINLVA PSTLDDLWRR HILDSIQLFQ 70 80 90 100 110 120 LSPAPKTWVD LGSGGGFPGV ITAICLSETE SGWVHLVESN NKKAAFLRVA LRETAARGTV 130 140 150 160 170 180 HPIRIEEAPA EIPTCDAISA RALSDLSQLL EYCAPWMTVE ASRTIAFFHK GRDYQLEIDK 190 200 210 AVSRFQFDLV KHASVVEPDS VVLEVANLSR RTK

References

[1]

"Complete sequence of Sinorhizobium medicae WSM419 chromosome." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM419.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000738 Genomic DNA. Translation: ABR62027.1.
RefSeq	YP_001328862.1. NC_009636.1.
3D structure databases
ProteinModelPortal	A6UEE7.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UEE7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5324082.
GenomeReviews	Gene locus Smed_3203 in contig CP000738_GR.
KEGG	smd:Smed_3203.
PATRIC	23625647. VBISinMed134228_6441.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0357.
HOGENOM	HBG686577.
OMA	GGQGWIV.
ProtClustDB	PRK00107.
Enzyme and pathway databases
BioCyc	SMED366394:SMED_3203-MONOMER.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G. [Tree]
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
KO	K03501.
Pfam	PF02527. GidB. 1 hit. [Graphical view]
PIRSF	PIRSF003078. GidB. 1 hit.
TIGRFAMs	TIGR00138. GidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_SINMW

Accession

Primary (citable) accession number: A6UEE7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program