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Protein

Ribosomal RNA small subunit methyltransferase G

Gene

rsmG

Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei72 – 721S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei77 – 771S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei141 – 1411S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSMED366394:GJAL-3255-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase GUniRule annotation (EC:2.1.1.170UniRule annotation)
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferaseUniRule annotation
Short name:
16S rRNA m7G methyltransferaseUniRule annotation
Gene namesi
Name:rsmGUniRule annotation
Ordered Locus Names:Smed_3203
OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)
Taxonomic identifieri366394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001108 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 213213Ribosomal RNA small subunit methyltransferase GPRO_1000010211Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi366394.Smed_3203.

Structurei

3D structure databases

ProteinModelPortaliA6UEE7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni125 – 1262S-adenosyl-L-methionine bindingUniRule annotation

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107YTN. Bacteria.
COG0357. LUCA.
HOGENOMiHOG000221015.
KOiK03501.
OMAiKCAFLSE.
OrthoDBiPOG091H00IF.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00074. 16SrRNA_methyltr_G. 1 hit.
InterProiIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02527. GidB. 1 hit.
[Graphical view]
PIRSFiPIRSF003078. GidB. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00138. rsmG_gidB. 1 hit.

Sequencei

Sequence statusi: Complete.

A6UEE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTSLNRALN GLRVSRETVE KLEHFASLFQ KWARSINLVA PSTLDDLWRR
60 70 80 90 100
HILDSIQLFQ LSPAPKTWVD LGSGGGFPGV ITAICLSETE SGWVHLVESN
110 120 130 140 150
NKKAAFLRVA LRETAARGTV HPIRIEEAPA EIPTCDAISA RALSDLSQLL
160 170 180 190 200
EYCAPWMTVE ASRTIAFFHK GRDYQLEIDK AVSRFQFDLV KHASVVEPDS
210
VVLEVANLSR RTK
Length:213
Mass (Da):23,781
Last modified:August 21, 2007 - v1
Checksum:i32E6AD7253E14C3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000738 Genomic DNA. Translation: ABR62027.1.
RefSeqiWP_012067408.1. NC_009636.1.
YP_001328862.1. NC_009636.1.

Genome annotation databases

EnsemblBacteriaiABR62027; ABR62027; Smed_3203.
GeneIDi5324082.
KEGGismd:Smed_3203.
PATRICi23625647. VBISinMed134228_6441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000738 Genomic DNA. Translation: ABR62027.1.
RefSeqiWP_012067408.1. NC_009636.1.
YP_001328862.1. NC_009636.1.

3D structure databases

ProteinModelPortaliA6UEE7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi366394.Smed_3203.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR62027; ABR62027; Smed_3203.
GeneIDi5324082.
KEGGismd:Smed_3203.
PATRICi23625647. VBISinMed134228_6441.

Phylogenomic databases

eggNOGiENOG4107YTN. Bacteria.
COG0357. LUCA.
HOGENOMiHOG000221015.
KOiK03501.
OMAiKCAFLSE.
OrthoDBiPOG091H00IF.

Enzyme and pathway databases

BioCyciSMED366394:GJAL-3255-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00074. 16SrRNA_methyltr_G. 1 hit.
InterProiIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02527. GidB. 1 hit.
[Graphical view]
PIRSFiPIRSF003078. GidB. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00138. rsmG_gidB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRSMG_SINMW
AccessioniPrimary (citable) accession number: A6UEE7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.