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A6UCZ1 (A6UCZ1_SINMW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Smed_2691
OrganismSinorhizobium medicae (strain WSM419) (Ensifer medicae) [Complete proteome] [HAMAP]
Taxonomic identifier366394 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2141Iron By similarity HAMAP MF_00323
Metal binding2951Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A6UCZ1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 50C1C48F189C996D

FASTA34539,339
        10         20         30         40         50         60 
MTAMEAEPNT NHPAVSYGKL GVLLVNLGTP DGTDVTSMRR YLREFLSDRR VIEWSRLFWY 

        70         80         90        100        110        120 
PILYGIVLNT RPRKVGKAYE LIWNKELNES WLRTYTRNQA ALMTEAFGGQ PQVIVDWAMR 

       130        140        150        160        170        180 
YGRPSIASRL DALQKAGCER ILVFPLYPQY AAATTATVND KAFEALLGMR WQPALRTVPP 

       190        200        210        220        230        240 
YHDDPVYIDA LATSITKHLA TLDWEPELVL ASFHGIPKSY FEKGDPYYCQ CQKTARLLRE 

       250        260        270        280        290        300 
RLGWPKEKLQ ITFQSRFGPE EWLQPYTDAT VERLAKEGVK KIAVINPGFV SDCLETLEEI 

       310        320        330        340 
AGQAAESFHH NGGEKFAHIP CLNDSPEGMA VLNHVVRREL EGWLY

« Hide

References

[1]"Complete sequence of Sinorhizobium medicae WSM419 chromosome."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WSM419.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000738 Genomic DNA. Translation: ABR61521.1.
RefSeqYP_001328356.1. NC_009636.1.

3D structure databases

ProteinModelPortalA6UCZ1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6UCZ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5323560.
GenomeReviewsGene locus Smed_2691 in contig CP000738_GR.
KEGGsmd:Smed_2691.
PATRIC23624527. VBISinMed134228_5892.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMATIEEIGM.
ProtClustDBPRK00035.

Enzyme and pathway databases

BioCycSMED366394:SMED_2691-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6UCZ1_SINMW
AccessionPrimary (citable) accession number: A6UCZ1
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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