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A6UCB5

- GPI_SINMW

UniProt

A6UCB5 - GPI_SINMW

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Protein

Glucose-6-phosphate isomerase

Gene
pgiA, Smed_2463
Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi92 – 921Iron By similarity
Metal bindingi94 – 941Iron By similarity
Metal bindingi101 – 1011Iron By similarity
Metal bindingi140 – 1401Iron By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
  2. iron ion binding Source: InterPro

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

BioCyciSMED366394:GJAL-2497-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgiA
Ordered Locus Names:Smed_2463
OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)
Taxonomic identifieri366394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001108: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214Glucose-6-phosphate isomeraseUniRule annotationPRO_1000068451Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi366394.Smed_2463.

Structurei

3D structure databases

ProteinModelPortaliA6UCB5.

Family & Domainsi

Sequence similaritiesi

Belongs to the archaeal-type GPI family.

Phylogenomic databases

eggNOGiCOG2140.
HOGENOMiHOG000243903.
KOiK06859.
OrthoDBiEOG6M6JRR.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
HAMAPiMF_01410. G6P_isomerase_arch.
InterProiIPR010551. G6P_isomerase_prok.
IPR016758. G6P_isomerase_subgr.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF06560. GPI. 1 hit.
[Graphical view]
PIRSFiPIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
SUPFAMiSSF51182. SSF51182. 1 hit.

Sequencei

Sequence statusi: Complete.

A6UCB5-1 [UniParc]FASTAAdd to Basket

« Hide

MTKLFEPAAC QVDLRTGAMS AATGAYQKRF RDLAGLYADE AAFSAMRENW    50
NDTVVYEVSE FRPNERSGDL IFGTTRMLPG KVGDEYFVTR GHIHRQSDRP 100
EIYYGQKGSG LMLLESPEGE VRIVAIDART VCYVPPYWIH RSVNIGGEEL 150
VMLFCYPADS GQDYDCIAKA GGMRVRIVDD GEGGWKQVDN SSWRKRDAAT 200
IAALYGLEKK EKSA 214
Length:214
Mass (Da):23,911
Last modified:August 21, 2007 - v1
Checksum:i6A2E7CA62D19768B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000738 Genomic DNA. Translation: ABR61295.1.
RefSeqiYP_001328130.1. NC_009636.1.

Genome annotation databases

EnsemblBacteriaiABR61295; ABR61295; Smed_2463.
GeneIDi5323324.
KEGGismd:Smed_2463.
PATRICi23624025. VBISinMed134228_5649.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000738 Genomic DNA. Translation: ABR61295.1 .
RefSeqi YP_001328130.1. NC_009636.1.

3D structure databases

ProteinModelPortali A6UCB5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 366394.Smed_2463.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR61295 ; ABR61295 ; Smed_2463 .
GeneIDi 5323324.
KEGGi smd:Smed_2463.
PATRICi 23624025. VBISinMed134228_5649.

Phylogenomic databases

eggNOGi COG2140.
HOGENOMi HOG000243903.
KOi K06859.
OrthoDBi EOG6M6JRR.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci SMED366394:GJAL-2497-MONOMER.

Family and domain databases

Gene3Di 2.60.120.10. 1 hit.
HAMAPi MF_01410. G6P_isomerase_arch.
InterProi IPR010551. G6P_isomerase_prok.
IPR016758. G6P_isomerase_subgr.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view ]
Pfami PF06560. GPI. 1 hit.
[Graphical view ]
PIRSFi PIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
SUPFAMi SSF51182. SSF51182. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Sinorhizobium medicae WSM419 chromosome."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P.
    Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WSM419.

Entry informationi

Entry nameiGPI_SINMW
AccessioniPrimary (citable) accession number: A6UCB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: June 11, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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