A6UB96 (DADA_SINMW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	Smed_2093

Organism

Sinorhizobium medicae (strain WSM419) (Ensifer medicae) [Complete proteome] [HAMAP]

Taxonomic identifier

366394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	416 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 416	416	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_1000066120
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	A6UB96 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 77DDA7D0EB49BFD5	FASTA	416	44,828
	10 20 30 40 50 60 MKVIVLGAGI IGVTSAYQLS RAGHEVTVID RQPGPALETS FANAGEVSFG YCSPWAAPGI 70 80 90 100 110 120 PMKALKWLFM QHAPLILRPR IDAAMLSWMA KMLSNCTSRR YAVNKSRMLR LADYSRTSLA 130 140 150 160 170 180 ALREETAITY DERMQGTLQL FRTEAQLDAS AKDISALAAD GIPYEVLDRD GCIRAEPALG 190 200 210 220 230 240 RVRDKIVGGL LTPQDETGDC FKFANALAGR AEKLGVCFDY GTEIRALEVD GGRVHGVVTS 250 260 270 280 290 300 KGRRAADAVV VALGSYSPLL VRRFGIRLPV YPVKGYSLTI PIADASRAPV STVMDETYKI 310 320 330 340 350 360 AITRLGDRIR VGGMAEISGY TNDLGIARRR TLEHSVMDLF PGGDAAKGSF WSGLRPMTPD 370 380 390 400 410 GTPVIGPTRI AGLFLNTGHG TLGWTMSSGS ARVIADLVSD RKLEIDATDL AIARYG

References

[1]

"Complete sequence of Sinorhizobium medicae WSM419 chromosome." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM419.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000738 Genomic DNA. Translation: ABR60926.1.
RefSeq	YP_001327761.1. NC_009636.1.
3D structure databases
ProteinModelPortal	A6UB96.
ModBase	Search...
Protein-protein interaction databases
STRING	A6UB96.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5322953.
GenomeReviews	Gene locus Smed_2093 in contig CP000738_GR.
KEGG	smd:Smed_2093.
PATRIC	23623227. VBISinMed134228_5251.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0665.
HOGENOM	HBG729204.
OMA	VDRQPAV.
ProtClustDB	PRK00711.
Enzyme and pathway databases
BioCyc	SMED366394:SMED_2093-MONOMER.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_SINMW

Accession

Primary (citable) accession number: A6UB96

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program