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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei141GTPUniRule annotation1
Binding sitei145GTPUniRule annotation1
Binding sitei189GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 27GTPUniRule annotation5
Nucleotide bindingi110 – 112GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Smed_1943Imported
OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)Imported
Taxonomic identifieri366394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001108 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi366394.Smed_1943.

Structurei

3D structure databases

ProteinModelPortaliA6UAU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 207TubulinInterPro annotationAdd BLAST193
Domaini209 – 327Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A6UAU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKKPVIT EMRPKITVIG VGGGGGNAIN NMIAENLQGV DFIAANTDAQ
60 70 80 90 100
ALATSKAERR IQLGAAITEG LGAGSVPDIG NAAAQESIDE IMDHLGGTHM
110 120 130 140 150
CFVTAGMGGG TGTGAAPVIA EAARRAGILT VAVVTKPFSF EGQRRMQTAE
160 170 180 190 200
LGVDRLRESA DTVIVIPNQN LFRIADAKTT FADAFMIADR VLYSGVSCIT
210 220 230 240 250
DLIVKEGLMN LDFADVKTVM KGMGRAMMGT GEATGENRAM MAAEAAIANP
260 270 280 290 300
LLDEVSMRGA KGVLVSISGG MDMTLFEVDE AATRIREEVY DEADIVVGAI
310 320 330 340
FDRSLDGTFR VSVVATGLDG NRGAQATAPE AMNGQAAAVP TRTLQ
Length:345
Mass (Da):35,937
Last modified:August 21, 2007 - v1
Checksum:i8AC9C6DBD7269967
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000738 Genomic DNA. Translation: ABR60777.1.
RefSeqiWP_011976076.1. NC_009636.1.
YP_001327612.1. NC_009636.1.

Genome annotation databases

EnsemblBacteriaiABR60777; ABR60777; Smed_1943.
GeneIDi5322802.
KEGGismd:Smed_1943.
PATRICifig|366394.8.peg.5095.

Similar proteinsi

Entry informationi

Entry nameiA6UAU7_SINMW
AccessioniPrimary (citable) accession number: A6UAU7
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: September 27, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported