Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Trans-aconitate 2-methyltransferase

Gene

tam

Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSMED366394:GJAL-590-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Trans-aconitate 2-methyltransferaseUniRule annotation (EC:2.1.1.144UniRule annotation)
Gene namesi
Name:tamUniRule annotation
Ordered Locus Names:Smed_0581
OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)
Taxonomic identifieri366394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001108 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 257257Trans-aconitate 2-methyltransferasePRO_1000056583Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi366394.Smed_0581.

Structurei

3D structure databases

ProteinModelPortaliA6U707.
SMRiA6U707. Positions 5-256.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. Tam family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiETTYLHV.
OrthoDBiPOG091H08XS.

Family and domain databases

Gene3Di1.10.150.290. 2 hits.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

A6U707-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAWSAAQYTK FEDERTRPAR DLLAQVTELP DGPAFDLGCG PGNSTELILN
60 70 80 90 100
RFRDNPLTGI DSDEDMLSAA RTRLPELRFE KADLASWVPP AESALFFANA
110 120 130 140 150
VFQWLPEHIV LFERLILALA PGGTLAVQMP DNLDEPTHVL MEETAEESAF
160 170 180 190 200
ASAFAGRAAR RKSLPSPANY VERLTAKDVR IDVWHTVYYH QLANANAIVE
210 220 230 240 250
WVKGTGLRPY LDALPAARRA GYLAAYADKI RKAYPTMKDG RVLLRFPRLF

IVATRNR
Length:257
Mass (Da):28,758
Last modified:August 21, 2007 - v1
Checksum:i7BD00E943E192F73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000738 Genomic DNA. Translation: ABR59437.1.
RefSeqiWP_011974783.1. NC_009636.1.
YP_001326272.1. NC_009636.1.

Genome annotation databases

EnsemblBacteriaiABR59437; ABR59437; Smed_0581.
GeneIDi5321417.
KEGGismd:Smed_0581.
PATRICi23620024. VBISinMed134228_3674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000738 Genomic DNA. Translation: ABR59437.1.
RefSeqiWP_011974783.1. NC_009636.1.
YP_001326272.1. NC_009636.1.

3D structure databases

ProteinModelPortaliA6U707.
SMRiA6U707. Positions 5-256.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi366394.Smed_0581.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR59437; ABR59437; Smed_0581.
GeneIDi5321417.
KEGGismd:Smed_0581.
PATRICi23620024. VBISinMed134228_3674.

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiETTYLHV.
OrthoDBiPOG091H08XS.

Enzyme and pathway databases

BioCyciSMED366394:GJAL-590-MONOMER.

Family and domain databases

Gene3Di1.10.150.290. 2 hits.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTAM_SINMW
AccessioniPrimary (citable) accession number: A6U707
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.