A6U6U8 (COXZ_SINMW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase assembly protein CtaG

Gene names

Name:	ctaG
Ordered Locus Names:	Smed_0522

Organism

Sinorhizobium medicae (strain WSM419) (Ensifer medicae) [Complete proteome] [HAMAP]

Taxonomic identifier

366394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity. HAMAP MF_00155
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side Potential HAMAP MF_00155.
Sequence similarities	Belongs to the COX11/CtaG family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Ligand	Copper
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 198	198	Cytochrome c oxidase assembly protein CtaG HAMAP MF_00155		PRO_0000311209
Regions
	Topological domain	1 – 12	12	Cytoplasmic Potential
	Transmembrane	13 – 35	23	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	36 – 198	163	Periplasmic Potential

Sequences

	Sequence		Length	Mass (Da)
	A6U6U8 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: ED2B7B7F52AB7B12	FASTA	198	21,920
	10 20 30 40 50 60 MADTGQSDRK ERSNGVIVGT CLAFVVGMVG MAYAAVPLYD MFCRVTGYNG TTQRVEQESD 70 80 90 100 110 120 LILDEKVKVT FDANVAAGLP WEFAPVQRDI DVRIGETVQI TYRARNLAST PTTGQATFNV 130 140 150 160 170 180 TPMAAGAYFN KVQCFCFTET TLQPGEEMEM PVVFFVDPEI VKTVETKGIK TLTLSYTFYP 190 REPSKPVAQV KSRTENKL

References

[1]

"Complete sequence of Sinorhizobium medicae WSM419 chromosome." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM419.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000738 Genomic DNA. Translation: ABR59378.1.
RefSeq	YP_001326213.1. NC_009636.1.
3D structure databases
ProteinModelPortal	A6U6U8.
SMR	A6U6U8. Positions 55-185.
ModBase	Search...
Protein-protein interaction databases
STRING	A6U6U8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5321356.
GenomeReviews	Gene locus Smed_0522 in contig CP000738_GR.
KEGG	smd:Smed_0522.
PATRIC	23619890. VBISinMed134228_3609.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3175.
HOGENOM	HBG525908.
OMA	KLIFYRA.
ProtClustDB	PRK05089.
Enzyme and pathway databases
BioCyc	SMED366394:SMED_0522-MONOMER.
Family and domain databases
HAMAP	MF_00155. CtaG. [Tree]
InterPro	IPR023471. CtaG/Cox11_dom. IPR007533. Cyt_c_oxidase_assmbl_CtaG. [Graphical view]
Gene3D	G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.
KO	K02258.
PANTHER	PTHR21320. CtaG_Cox11. 1 hit.
Pfam	PF04442. CtaG_Cox11. 1 hit. [Graphical view]
PIRSF	PIRSF005413. COX11. 1 hit.
SUPFAM	SSF110111. CtaG_Cox11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COXZ_SINMW

Accession

Primary (citable) accession number: A6U6U8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 13, 2007
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program