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A6U5N9

- G6PI_SINMW

UniProt

A6U5N9 - G6PI_SINMW

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei346 – 3461Proton donorUniRule annotation
Active sitei377 – 3771UniRule annotation
Active sitei506 – 5061UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSMED366394:GJAL-110-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Smed_0109
OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)
Taxonomic identifieri366394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001108: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 541541Glucose-6-phosphate isomerasePRO_1000014023Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi366394.Smed_0109.

Structurei

3D structure databases

ProteinModelPortaliA6U5N9.
SMRiA6U5N9. Positions 15-538.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiRAHYVSN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6U5N9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKALVENLKA TARETDATDI RAAFAADPNR FSRFSTALDD LLFDYSKCAV
60 70 80 90 100
NDRIIDGLEA LAKAAKVEEK RDAMFRGDII NITEERAVLH TALRNRSNRP
110 120 130 140 150
VLVDGKNVVP DVNAVLEAMG RFADHVRSGD LKGATGKKIT DVVNIGIGGS
160 170 180 190 200
DLGPVMATLA LAPFHDGPRL HFVSNVDGAH IADTLKLLDA ETSLFIVASK
210 220 230 240 250
TFTTIETMTN AATARAFIAG KLGEAAVGHH FAAVSTALDK VGAFGINAAR
260 270 280 290 300
VFGFWDWVGG RYSIWSAIGL PLMIAIGKEN FGRFLDGGHS MDEHFRAAPL
310 320 330 340 350
RQNIPVLLGL IGFYNRNVLG YPSRAILPYD QRLTRFPAYL QQLDMESNGK
360 370 380 390 400
GVTLESQPVE FSTGPVVWGE PGTNGQHAFY QLIHQGTDII PAEFMIAAKG
410 420 430 440 450
HEKDLRHQHQ LLIANCLAQS EALMKGRTLA EAKAQLTSKG MDEAKADKIA
460 470 480 490 500
PHRVFTGNRP SLTIVYDQLD PFALGRLIAL YEHRVFVEGA LFNINSFDQW
510 520 530 540
GVELGKELAT GLLPVVEGRE SAEGHDSSTT GLVAALLKAA R
Length:541
Mass (Da):58,692
Last modified:August 21, 2007 - v1
Checksum:i43550C9B2C1ECFE7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000738 Genomic DNA. Translation: ABR58969.1.
RefSeqiYP_001325804.1. NC_009636.1.

Genome annotation databases

EnsemblBacteriaiABR58969; ABR58969; Smed_0109.
GeneIDi5320937.
KEGGismd:Smed_0109.
PATRICi23618989. VBISinMed134228_3165.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000738 Genomic DNA. Translation: ABR58969.1 .
RefSeqi YP_001325804.1. NC_009636.1.

3D structure databases

ProteinModelPortali A6U5N9.
SMRi A6U5N9. Positions 15-538.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 366394.Smed_0109.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR58969 ; ABR58969 ; Smed_0109 .
GeneIDi 5320937.
KEGGi smd:Smed_0109.
PATRICi 23618989. VBISinMed134228_3165.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi RAHYVSN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci SMED366394:GJAL-110-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Sinorhizobium medicae WSM419 chromosome."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P.
    Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WSM419.

Entry informationi

Entry nameiG6PI_SINMW
AccessioniPrimary (citable) accession number: A6U5N9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3