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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Staphylococcus aureus (strain JH1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei39NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:SaurJH1_1357
OrganismiStaphylococcus aureus (strain JH1)
Taxonomic identifieri359787 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000846891 – 305tRNA pseudouridine synthase BAdd BLAST305

Structurei

3D structure databases

ProteinModelPortaliA6U190
SMRiA6U190
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

A6U190-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYNGILPVYK ERGLTSHDVV FKLRKILKTK KIGHTGTLDP EVAGVLPVCI
60 70 80 90 100
GNATRVSDYV MDMGKAYEAT VSIGRSTTTE DQTGDTLETK GVHSADFNKD
110 120 130 140 150
DIDRLLENFK GVIEQIPPMY SSVKVNGKKL YEYARNNETV ERPKRKVNIK
160 170 180 190 200
DIGRISELDF KENECHFKIR VICGKGTYIR TLATDIGVKL GFPAHMSKLT
210 220 230 240 250
RIESGGFVLK DSLTLEQIKE LHEQDSLQNK LFPLEYGLKG LPSIKIKDSH
260 270 280 290 300
IKKRILNGQK FNKNEFDNKI KDQIVFIDDD SEKVLAIYMV HPTKESEIKP

KKVFN
Length:305
Mass (Da):34,606
Last modified:August 21, 2007 - v1
Checksum:i59510CA2C74F3F34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000736 Genomic DNA Translation: ABR52208.1
RefSeqiWP_000282298.1, NC_009632.1

Genome annotation databases

EnsemblBacteriaiABR52208; ABR52208; SaurJH1_1357
KEGGisah:SaurJH1_1357

Similar proteinsi

Entry informationi

Entry nameiTRUB_STAA2
AccessioniPrimary (citable) accession number: A6U190
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: March 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health