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A6U190

- TRUB_STAA2

UniProt

A6U190 - TRUB_STAA2

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Protein

tRNA pseudouridine synthase B

Gene
truB, SaurJH1_1357
Organism
Staphylococcus aureus (strain JH1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Nucleophile By similarity

GO - Molecular functioni

  1. pseudouridine synthase activity Source: UniProtKB-HAMAP
  2. RNA binding Source: InterPro

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciSAUR359787:GCG4-1383-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase B (EC:5.4.99.25)
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name:
Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene namesi
Name:truB
Ordered Locus Names:SaurJH1_1357
OrganismiStaphylococcus aureus (strain JH1)
Taxonomic identifieri359787 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001109: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 305305tRNA pseudouridine synthase BUniRule annotationPRO_1000084689Add
BLAST

Proteomic databases

PRIDEiA6U190.

Interactioni

Protein-protein interaction databases

STRINGi359787.SaurJH1_1357.

Structurei

3D structure databases

ProteinModelPortaliA6U190.
SMRiA6U190. Positions 1-287.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

A6U190-1 [UniParc]FASTAAdd to Basket

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MYNGILPVYK ERGLTSHDVV FKLRKILKTK KIGHTGTLDP EVAGVLPVCI    50
GNATRVSDYV MDMGKAYEAT VSIGRSTTTE DQTGDTLETK GVHSADFNKD 100
DIDRLLENFK GVIEQIPPMY SSVKVNGKKL YEYARNNETV ERPKRKVNIK 150
DIGRISELDF KENECHFKIR VICGKGTYIR TLATDIGVKL GFPAHMSKLT 200
RIESGGFVLK DSLTLEQIKE LHEQDSLQNK LFPLEYGLKG LPSIKIKDSH 250
IKKRILNGQK FNKNEFDNKI KDQIVFIDDD SEKVLAIYMV HPTKESEIKP 300
KKVFN 305
Length:305
Mass (Da):34,606
Last modified:August 21, 2007 - v1
Checksum:i59510CA2C74F3F34
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000736 Genomic DNA. Translation: ABR52208.1.
RefSeqiYP_001316495.1. NC_009632.1.

Genome annotation databases

EnsemblBacteriaiABR52208; ABR52208; SaurJH1_1357.
GeneIDi5315482.
KEGGisah:SaurJH1_1357.
PATRICi19534564. VBIStaAur98826_1391.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000736 Genomic DNA. Translation: ABR52208.1 .
RefSeqi YP_001316495.1. NC_009632.1.

3D structure databases

ProteinModelPortali A6U190.
SMRi A6U190. Positions 1-287.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359787.SaurJH1_1357.

Proteomic databases

PRIDEi A6U190.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR52208 ; ABR52208 ; SaurJH1_1357 .
GeneIDi 5315482.
KEGGi sah:SaurJH1_1357.
PATRICi 19534564. VBIStaAur98826_1391.

Phylogenomic databases

eggNOGi COG0130.
HOGENOMi HOG000231225.
KOi K03177.
OMAi YELQFIR.
OrthoDBi EOG6358D3.

Enzyme and pathway databases

BioCyci SAUR359787:GCG4-1383-MONOMER.

Family and domain databases

HAMAPi MF_01080. TruB_bact.
InterProi IPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view ]
PANTHERi PTHR13767. PTHR13767. 1 hit.
Pfami PF01509. TruB_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00431. TruB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Staphylococcus aureus subsp. aureus JH1."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.
    , Hauser L., Kyrpides N., Ivanova N., Tomasz A., Richardson P.
    Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JH1.

Entry informationi

Entry nameiTRUB_STAA2
AccessioniPrimary (citable) accession number: A6U190
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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