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A6U190

- TRUB_STAA2

UniProt

A6U190 - TRUB_STAA2

Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Staphylococcus aureus (strain JH1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (21 Aug 2007)
      Previous versions | rss
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    • Comment

    Functioni

    Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei39 – 391NucleophileUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciSAUR359787:GCG4-1383-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(55) synthaseUniRule annotation
    Short name:
    Psi55 synthaseUniRule annotation
    tRNA pseudouridylate synthaseUniRule annotation
    tRNA-uridine isomeraseUniRule annotation
    Gene namesi
    Name:truBUniRule annotation
    Ordered Locus Names:SaurJH1_1357
    OrganismiStaphylococcus aureus (strain JH1)
    Taxonomic identifieri359787 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000001109: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 305305tRNA pseudouridine synthase BPRO_1000084689Add
    BLAST

    Proteomic databases

    PRIDEiA6U190.

    Interactioni

    Protein-protein interaction databases

    STRINGi359787.SaurJH1_1357.

    Structurei

    3D structure databases

    ProteinModelPortaliA6U190.
    SMRiA6U190. Positions 1-287.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0130.
    HOGENOMiHOG000231225.
    KOiK03177.
    OMAiYELQFIR.
    OrthoDBiEOG6358D3.

    Family and domain databases

    HAMAPiMF_01080. TruB_bact.
    InterProiIPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view]
    PANTHERiPTHR13767. PTHR13767. 1 hit.
    PfamiPF01509. TruB_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00431. TruB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6U190-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYNGILPVYK ERGLTSHDVV FKLRKILKTK KIGHTGTLDP EVAGVLPVCI    50
    GNATRVSDYV MDMGKAYEAT VSIGRSTTTE DQTGDTLETK GVHSADFNKD 100
    DIDRLLENFK GVIEQIPPMY SSVKVNGKKL YEYARNNETV ERPKRKVNIK 150
    DIGRISELDF KENECHFKIR VICGKGTYIR TLATDIGVKL GFPAHMSKLT 200
    RIESGGFVLK DSLTLEQIKE LHEQDSLQNK LFPLEYGLKG LPSIKIKDSH 250
    IKKRILNGQK FNKNEFDNKI KDQIVFIDDD SEKVLAIYMV HPTKESEIKP 300
    KKVFN 305
    Length:305
    Mass (Da):34,606
    Last modified:August 21, 2007 - v1
    Checksum:i59510CA2C74F3F34
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000736 Genomic DNA. Translation: ABR52208.1.
    RefSeqiYP_001316495.1. NC_009632.1.

    Genome annotation databases

    EnsemblBacteriaiABR52208; ABR52208; SaurJH1_1357.
    GeneIDi5315482.
    KEGGisah:SaurJH1_1357.
    PATRICi19534564. VBIStaAur98826_1391.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000736 Genomic DNA. Translation: ABR52208.1 .
    RefSeqi YP_001316495.1. NC_009632.1.

    3D structure databases

    ProteinModelPortali A6U190.
    SMRi A6U190. Positions 1-287.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359787.SaurJH1_1357.

    Proteomic databases

    PRIDEi A6U190.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR52208 ; ABR52208 ; SaurJH1_1357 .
    GeneIDi 5315482.
    KEGGi sah:SaurJH1_1357.
    PATRICi 19534564. VBIStaAur98826_1391.

    Phylogenomic databases

    eggNOGi COG0130.
    HOGENOMi HOG000231225.
    KOi K03177.
    OMAi YELQFIR.
    OrthoDBi EOG6358D3.

    Enzyme and pathway databases

    BioCyci SAUR359787:GCG4-1383-MONOMER.

    Family and domain databases

    HAMAPi MF_01080. TruB_bact.
    InterProi IPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view ]
    PANTHERi PTHR13767. PTHR13767. 1 hit.
    Pfami PF01509. TruB_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00431. TruB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Staphylococcus aureus subsp. aureus JH1."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.
      , Hauser L., Kyrpides N., Ivanova N., Tomasz A., Richardson P.
      Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JH1.

    Entry informationi

    Entry nameiTRUB_STAA2
    AccessioniPrimary (citable) accession number: A6U190
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3