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A6TU96 (GLSA_ALKMQ) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Amet_3642
OrganismAlkaliphilus metalliredigens (strain QYMF) [Complete proteome] [HAMAP]
Taxonomic identifier293826 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeAlkaliphilus

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Glutaminase HAMAP-Rule MF_00313
PRO_0000336021

Sites

Binding site611Substrate By similarity
Binding site1131Substrate By similarity
Binding site1581Substrate By similarity
Binding site1651Substrate By similarity
Binding site1891Substrate By similarity
Binding site2411Substrate By similarity
Binding site2591Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A6TU96 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: E81102CDDBE3EB6D

FASTA30533,617
        10         20         30         40         50         60 
MNEQLQKILD TNRHHIQGGQ LPTYIPELSK ANKEALGIYV ADLDGNEYGV GDYEYPFTIQ 

        70         80         90        100        110        120 
SISKVVTLLL ALSDRGEKYV FDKVGMEPTG DPFNSMMKLE VVRPSKPFNP MINAGAIAVT 

       130        140        150        160        170        180 
SMIKGDSQKE RLERILGFFR QLTENPNLQV NQSVYRSEKI TGDRNRSMAY FMKDVGIMQN 

       190        200        210        220        230        240 
DIESDLDLYF NQCSIEVTCK DIAKIGRFLA NGGVLFETGQ QLIDEKYIKM AEAFMVTCGM 

       250        260        270        280        290        300 
YNASGEFAIK VGIPAKSGVG GGIMASVPKK MGIGVVGPSL DEKGNSIAGV RVLQKMAEDY 


GLSIF 

« Hide

References

[1]"Complete sequence of Alkaliphilus metalliredigens QYMF."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J., Fields M., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: QYMF.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000724 Genomic DNA. Translation: ABR49764.1.
RefSeqYP_001321423.1. NC_009633.1.

3D structure databases

ProteinModelPortalA6TU96.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING293826.Amet_3642.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR49764; ABR49764; Amet_3642.
GeneID5313723.
KEGGamt:Amet_3642.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycAMET293826:GI5P-3696-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_ALKMQ
AccessionPrimary (citable) accession number: A6TU96
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families