Reviewed, UniProtKB/Swiss-Prot A6TSC8 (GLGA_ALKMQ)

Names and origin

Protein names

Recommended name:
    Glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	Amet_2946

Organism

Alkaliphilus metalliredigens (strain QYMF) [Complete proteome] [HAMAP]

Taxonomic identifier

293826 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Alkaliphilus

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 475	475	Glycogen synthase HAMAP MF_00484		PRO_1000060429
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6TSC8-1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 3161656D6BB1A7B5	FASTA	475	54,590
	10 20 30 40 50 60 MRVMFAASEA TPFSKSGGLG DVIGSLPFYL KKLGVDVSVI LPKYQEIPQD LKMKMKWIKS 70 80 90 100 110 120 MTVPVGWRNQ FCGIEILSYK DIHFYFVDNQ YYFNREGFYG HNDDGERFAF FSRSVLEILP 130 140 150 160 170 180 HIDCKPDIIH CHDWQTAMIS YLLKTQYQHH GFYKNIKTVF TIHNLKYQGV FPQEVLGDLF 190 200 210 220 230 240 NGSQQHFNEG GVEYHGNVNY MKGGLNFSDY ITTVSPTYAQ EIQDPFFGEG LEGVLSRKKK 250 260 270 280 290 300 QLQGVTNGID DSVYNPQTDI HLFKNFSSEN LRNKKDNKLG LQERLNLAVD AKIPMIGMVT 310 320 330 340 350 360 RLVEQKGLDL VANQLEKLME EEIQLVVLGT GDHQYEEIFR QAAIKYPERI STNLFFDEVL 370 380 390 400 410 420 AQQIYGGSDF FLMPSLFEPC GLGQLIALRY GTVPIVRETG GLKDTIQYYD EVSKEGNGFT 430 440 450 460 470 FTNYNAHDMF NTIKEAIRLY PDKRKFNKVV RNAMNTKVGW EESAKTYLKL YRSLG

References

[1]

"Complete sequence of Alkaliphilus metalliredigens QYMF." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J., Fields M., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000724 Genomic DNA. Translation: ABR49096.1.
RefSeq	YP_001320755.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A6TSC8.
Genome annotation databases
GeneID	5313020.
GenomeReviews	Gene locus Amet_2946 in contig CP000724_GR.
KEGG	amt:Amet_2946.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	YQGPWRW.
Family and domain databases
HAMAP	MF_00484. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Glyco_transf_5. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_ALKMQ

Accession

Primary (citable) accession number: A6TSC8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	August 21, 2007
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)