A6TRG1 (KCY_ALKMQ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	Amet_2627

Organism

Alkaliphilus metalliredigens (strain QYMF) [Complete proteome] [HAMAP]

Taxonomic identifier

293826 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Alkaliphilus

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 220	220	Cytidylate kinase HAMAP MF_00238		PRO_1000119004
Regions
	Nucleotide binding	10 – 18	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6TRG1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: AD95600745DF8ADA	FASTA	220	24,375
	10 20 30 40 50 60 MTFKQIAIDG PAGAGKSTVA KKLAALLGYT YVDSGAMYRA LTYWALKNDI NIHNVEAIVN 70 80 90 100 110 120 LCTSIHITFI NQDIAVNNQI VNTEIRSPEV NNNVSHIAKI PEVRKHLVSL QKCIALSQNV 130 140 150 160 170 180 IMDGRDIGTH VLPDADIKVF LTASTQERAQ RRYIELVEKG IQTSLMEVEQ GIIQRDQMDS 190 200 210 220 KRQYAPLTQA DDAVVIDSTG KSIDAIVEEV LRIFNGKERG

References

[1]

"Complete sequence of Alkaliphilus metalliredigens QYMF." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J., Fields M., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: QYMF.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000724 Genomic DNA. Translation: ABR48779.1.
RefSeq	YP_001320438.1. NC_009633.1.
3D structure databases
ProteinModelPortal	A6TRG1.
ModBase	Search...
Protein-protein interaction databases
STRING	A6TRG1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5312699.
GenomeReviews	Gene locus Amet_2627 in contig CP000724_GR.
KEGG	amt:Amet_2627.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0283.
HOGENOM	HBG354377.
OMA	DIGTVIC.
Enzyme and pathway databases
BioCyc	AMET293826:AMET_2627-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_ALKMQ

Accession

Primary (citable) accession number: A6TRG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program