Unreviewed, UniProtKB/TrEMBL A6TJ90 (A6TJ90_ALKMQ)

Names and origin

Protein names

Submitted name:
Glycine dehydrogenase (Decarboxylating) EMBL ABR46258.1
EC=1.4.4.2 EMBL ABR46258.1

Gene names

Ordered Locus Names:

Amet_0015

Organism

Alkaliphilus metalliredigens (strain QYMF) [Complete proteome] [HAMAP]

Taxonomic identifier

293826 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Alkaliphilus

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity. Spearmint SPM020581
Catalytic activity	Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2. Spearmint SPM020581
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is an heterodimer of two subunits By similarity. Spearmint SPM020581

Ontologies

Keywords
Molecular function	Oxidoreductase Spearmint SPM020581 EMBL ABR46258.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glycine dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6TJ90-1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: D3D11FBAF56C6067	FASTA	447	49,949
	10 20 30 40 50 60 MFPYIPATEE SKKKMLEDVG LNSVEDLFKD ISHKVRLKGE LNIPKHKSEL EVSSYIKKLG 70 80 90 100 110 120 KMNETTEDYT CFLGCGAYDH YIPSVVDAVI SRSEYYTAYT PYQAEIAQGT LQTIFEFQSM 130 140 150 160 170 180 MAGLTGMDVC NASVYDGSTA VYEAAYVAVA SNRRKEVLIS KSVHPEYRKV LKASLGAANI 190 200 210 220 230 240 KYIEIEIKEG TTDLDDLKEK LTKDVSAVIV QSPNFFGLIE EVEEVVKESH ENKSLVVMST 250 260 270 280 290 300 DPISLGLLKT PGEMGVDIAI GEAQALGIPL SFGGPYLGFI TTTKALLRKV PGRLVGMTKD 310 320 330 340 350 360 VDGKRGFVLT LQTREQHIRR EKSISNICTN QALNATAATV YLSLMGKEGM KEVAKQNYDK 370 380 390 400 410 420 AHYAHEQLIS TGMFEDSWEK PFFKEFTLKY KGNLKALKEK LEENKILGGF HPKEDYQALE 430 440 NHLIIAVTEK RSKEEVDQLC TIVKEVE

References

[1]

"Complete sequence of Alkaliphilus metalliredigens QYMF." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J., Fields M., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000724 Genomic DNA. Translation: ABR46258.1.
RefSeq	YP_001317917.1.
3D structure databases
SMR	A6TJ90. Positions 2-446.
ModBase	Search...
Protein-protein interaction databases
STRING	A6TJ90.
Genome annotation databases
GeneID	5310044.
GenomeReviews	Gene locus Amet_0015 in contig CP000724_GR.
KEGG	amt:Amet_0015.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0403.
HOGENOM	HBG288345.
OMA	ESHENKS.
Family and domain databases
InterPro	IPR020581. GDC-P-like. IPR020580. GDC-P_N. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
PANTHER	PTHR11773. GDC-P. 1 hit.
Pfam	PF02347. GDC-P. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6TJ90_ALKMQ

Accession

Primary (citable) accession number: A6TJ90

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	March 2, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)