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A6THY6 (RSMC_KLEP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase C
EC=2.1.1.172
Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC
Gene names
Name:rsmC
Ordered Locus Names:KPN78578_47460
ORF Names:KPN_04827
OrganismKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) [Complete proteome] [HAMAP]
Taxonomic identifier272620 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP MF_01862

Catalytic activity

S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1207) in 16S rRNA. HAMAP MF_01862

Subunit structure

Monomer By similarity. HAMAP MF_01862

Subcellular location

Cytoplasm Potential HAMAP MF_01862.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnucleic acid binding

Inferred from electronic annotation. Source: InterPro

rRNA (guanine-N2-)-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 342342Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862
PRO_0000369724

Sequences

Sequence LengthMass (Da)Tools
A6THY6 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: EC0DD991B1C69EF4

FASTA34237,360
        10         20         30         40         50         60 
MSAFTPASEV LLRHSDDFES ARVLFAGDLQ DDLPARLDTA ASRAHTQQFH HWQVLNRQMG 

        70         80         90        100        110        120 
DTVRFSLVAE AADVAECDTL IYYWPKNKPE AQFQLMNLLS LLPVGSDIFV VGENRSGVRS 

       130        140        150        160        170        180 
AEQMLAEYAP LNKVDSARRC GLYHGRLEKQ PTFDADAFWG EYTLDNLTIK TLPGVFSRDG 

       190        200        210        220        230        240 
LDVGSQLLLS TLEPHTKGKV LDVGCGAGVL AAALASHSPK VRLTLCDVSA PAVEASRATL 

       250        260        270        280        290        300 
AANGLAGDVF ASNVFSEVNG RFDMIISNPP FHDGLQTSLE AAQALIRGAV RHLNSGGELR 

       310        320        330        340 
IVANAFLPYP QVLDETFGFH EVIAQTGRFK VYRTIMTRQA KK

« Hide

References

[1]The Klebsiella pneumonia Genome Sequencing Project
McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700721 / MGH 78578.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000647 Genomic DNA. Translation: ABR80170.1.
RefSeqYP_001338437.1. NC_009648.1.

3D structure databases

ProteinModelPortalA6THY6.
SMRA6THY6. Positions 3-336.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6THY6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5342008.
GenomeReviewsGene locus KPN78578_47460 in contig CP000647_GR.
KEGGkpn:KPN_04827.
PATRIC20464128. VBIKlePne13394_4866.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2813.
HOGENOMHBG296757.
OMATGKFKVY.
ProtClustDBPRK09489.

Family and domain databases

HAMAPMF_01862. 16SrRNA_methyltr_C.
[Tree]
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR013675. Mtase_sm_N.
IPR023543. rRNA_ssu_MeTfrase_C.
IPR007848. Small_mtfrase.
[Graphical view]
KOK00564.
PfamPF05175. MTS. 1 hit.
PF08468. MTS_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRSMC_KLEP7
AccessionPrimary (citable) accession number: A6THY6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: August 21, 2007
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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