SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A6TGT4

- G6PI_KLEP7

UniProt

A6TGT4 - G6PI_KLEP7

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glucose-6-phosphate isomerase
Gene
pgi, KPN78578_43440, KPN_04413
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donor By similarity
Active sitei386 – 3861 By similarity
Active sitei514 – 5141 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciKPNE272620:GKDC-4450-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:KPN78578_43440
ORF Names:KPN_04413
OrganismiKlebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Taxonomic identifieri272620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000000265: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Glucose-6-phosphate isomeraseUniRule annotation
PRO_1000013976Add
BLAST

Proteomic databases

PRIDEiA6TGT4.

Interactioni

Protein-protein interaction databases

STRINGi272620.KPN_04413.

Structurei

3D structure databases

ProteinModelPortaliA6TGT4.
SMRiA6TGT4. Positions 7-548.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6TGT4-1 [UniParc]FASTAAdd to Basket

« Hide

MKNINPTQTS AWQALQKHFD EMKDVTISEL FAKDSDRFSK FSATFDDLML    50
VDFSKNRITE ETLAKLQDLA KETDLAGAIK SMFSGEKINR TEDRAVLHVA 100
LRNRSNTPIV VDGKDVMPEV NAVLEKMKTF SEAIISGSWK GYTGKPITDV 150
VNIGIGGSDL GPFMVTEALR PYKNHLNMHF VSNVDGTHIA EVLKNVNPET 200
TLFLVASKTF TTQETMTNAH SARDWFLATA GDDKHVAKHF AALSTNAKAV 250
GEFGIDTANM FEFWDWVGGR YSLWSAIGLS IILSVGFDNF VELLSGAHAM 300
DKHFSTTPAE KNLPVLLALI GIWYNNFFGA ETEAILPYDQ YMHRFAAYFQ 350
QGNMESNGKY VDRNGHAVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKMVP 400
CDFIAPAITH NPLSDHHQKL LSNFFAQTEA LAFGKSREVV EQEYRDQGKD 450
PATLEHVVPF KVFEGNRPTN SILLREITPF SLGALIALYE HKIFTQGAIL 500
NIFTFDQWGV ELGKQLANRI LPELKDGSEV SSHDSSTNGL INRYKAWRA 549
Length:549
Mass (Da):61,328
Last modified:August 21, 2007 - v1
Checksum:i8B300E5AF259BCDB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR79768.1.
RefSeqiYP_001338035.1. NC_009648.1.

Genome annotation databases

EnsemblBacteriaiABR79768; ABR79768; KPN_04413.
GeneIDi5342636.
KEGGikpn:KPN_04413.
PATRICi20463286. VBIKlePne13394_4457.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000647 Genomic DNA. Translation: ABR79768.1 .
RefSeqi YP_001338035.1. NC_009648.1.

3D structure databases

ProteinModelPortali A6TGT4.
SMRi A6TGT4. Positions 7-548.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272620.KPN_04413.

Proteomic databases

PRIDEi A6TGT4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR79768 ; ABR79768 ; KPN_04413 .
GeneIDi 5342636.
KEGGi kpn:KPN_04413.
PATRICi 20463286. VBIKlePne13394_4457.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci KPNE272620:GKDC-4450-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700721 / MGH 78578.

Entry informationi

Entry nameiG6PI_KLEP7
AccessioniPrimary (citable) accession number: A6TGT4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi